针灸在临床和动物研究中对神经系统疾病的影响。
Effects of Acupuncture on Neurological Disease in Clinical- and Animal-Based Research.
作者信息
Guo Xiangyu, Ma Tao
机构信息
Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
出版信息
Front Integr Neurosci. 2019 Aug 30;13:47. doi: 10.3389/fnint.2019.00047. eCollection 2019.
Abstract
Neurological disease, including Alzheimer's disease (AD), Parkinson's disease (PD), which were caused by abnormalities in the nervous system involves the accumulation of false proteins, neurotransmitter abnormalities, neuronal apoptosis, etc. As an alternative supplementary medicine (ASM), acupuncture plays an important role in the treatment of neurological diseases. In this review article, we summarized the current evidence for the treatment efficacy of acupuncture in AD and PD from the perspective of clinical trials and animal model. Acupuncture can inhibit the accumulation of toxic proteins in neurological diseases, modulate energy supply based on glucose metabolism, depress neuronal apoptosis, etc., and exert a wide range of neuroprotective effects.
摘要
神经系统疾病，包括阿尔茨海默病（AD）、帕金森病（PD），是由神经系统异常引起的，涉及错误蛋白质的积累、神经递质异常、神经元凋亡等。作为一种替代补充医学（ASM），针灸在神经系统疾病的治疗中发挥着重要作用。在这篇综述文章中，我们从临床试验和动物模型的角度总结了目前针灸治疗AD和PD疗效的证据。针灸可以抑制神经系统疾病中有毒蛋白质的积累，基于葡萄糖代谢调节能量供应，抑制神经元凋亡等，并发挥广泛的神经保护作用。
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