Jeong Eui-Suk, Park Jong-Hyung, Ryu Seung-Hyun, Choi Soo-Young, Lee Kyoung-Sun, Kim Jong-Man, Hyun Byung-Hwa, Choi Yang-Kyu
Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.
Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of Korea.
Iran J Parasitol. 2019 Apr-Jun;14(2):334-339.
Recently, the use of common marmoset () has increased in biomedical research as an animal model. This study aimed to test fecal samples to monitor bacterial and parasite infections in common marmoset at the Laboratory Animal Center of Osong Medical Innovation Foundation in Korea.
To monitor bacteria and parasites in common marmoset, we tested 43 fecal samples of 43 common marmosets by culture and parasitological test in 2014. Infection by was determined by PCR method.
We identified nonpathogenic bacteria such as and in feces of normal common marmosets. Interestingly, was isolated from a healthy common marmoset by fecal centrifugation concentration and PCR. The monkey infected with was treated with metronidazole. After the treatment, were not found in feces using fecal centrifugation concentration and PCR.
This is the first case report of infection in common marmoset. Treatment with metronidazole is found to be highly effective in eradicating infection in common marmoset.
近年来，普通狨猴作为动物模型在生物医学研究中的应用有所增加。本研究旨在对韩国峨山医学创新基金会实验动物中心的普通狨猴粪便样本进行检测，以监测其细菌和寄生虫感染情况。
为监测普通狨猴的细菌和寄生虫，2014年我们对43只普通狨猴的43份粪便样本进行了培养和寄生虫学检测。采用聚合酶链反应（PCR）方法检测[具体细菌名称未给出]感染情况。
我们在正常普通狨猴粪便中鉴定出非致病性细菌，如[具体细菌名称未给出]和[具体细菌名称未给出]。有趣的是，通过粪便离心浓缩和PCR从一只健康普通狨猴中分离出[具体细菌名称未给出]。感染[具体细菌名称未给出]的猴子用甲硝唑治疗。治疗后，通过粪便离心浓缩和PCR在粪便中未发现[具体细菌名称未给出]。
这是普通狨猴感染[具体细菌名称未给出]的首例病例报告。发现甲硝唑治疗在根除普通狨猴[具体细菌名称未给出]感染方面非常有效。
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