Nugent G R, Al-Mefty O, Chou S
J Neurosurg. 1979 Dec;51(6):812-8. doi: 10.3171/jns.1979.51.6.0812.
Eleven cases of presumed aqueductal stenosis with onset of symptoms after the first decade were reviewed. Ten patients had complete occlusion and one a high-grade stenosis. In 10, the dilated lateral ventricles caused a marked inferior displacement of the third ventricle. Postshunting diagnostic studies on six of these patients revealed ascent of the third ventricle, and in three of these the aqueduct was shown to be patent. It appears that in some cases of advanced communicating hydrocephalus the descending third ventricle kinks or pinches shut the aqueduct, adding an obstructive component which accelerates the clinical picture. The mechanism and clinical features of this process are discussed.
回顾了11例在十岁之后出现症状的疑似导水管狭窄病例。10例患者存在完全闭塞,1例为高度狭窄。在10例中,扩张的侧脑室导致第三脑室明显向下移位。对其中6例患者进行分流术后诊断性研究发现第三脑室上升,其中3例显示导水管通畅。看来在一些晚期交通性脑积水病例中,下降的第三脑室扭结或挤压导水管使其关闭,增加了梗阻成分,从而加速了临床表现。本文讨论了这一过程的机制和临床特征。