Jayadev Chaitra, Jain Nimesh, Sachdev Sonia, Mohan Ashwin, Yadav Naresh Kumar
Department of Vitreoretina, Narayana Nethralaya, Bengaluru, Karnataka, India.
Indian J Ophthalmol. 2016 Dec;64(12):940-943. doi: 10.4103/0301-4738.198850.
Fluorescein angiography (FFA) has been the gold standard to understand, diagnose and treat retinal disorders. However, being an invasive procedure it has several limitations including adverse drug reactions. Hence, noninvasive tests that can be repeated during the course of the disease are the need of the hour. The aim of our study was to compare images of patients with retinal microvasculature pathology taken from three different imaging modalities (invasive vs. noninvasive). Lesions were detected more easily and with a greater resolution of morphology on retinal function imaging (RFI) and optical coherence tomography angiography (angio-OCT). Functional integrity of the vessels was better delineated on FFA. RFI and angio-OCT are noninvasive rapid and efficient methods to image vascular conditions with easy repeatability and negligible adverse effects.
荧光素血管造影（FFA）一直是了解、诊断和治疗视网膜疾病的金标准。然而，作为一种侵入性检查，它有几个局限性，包括药物不良反应。因此，在疾病过程中可以重复进行的非侵入性检查是当务之急。我们研究的目的是比较从三种不同成像方式（侵入性与非侵入性）获取的视网膜微血管病变患者的图像。在视网膜功能成像（RFI）和光学相干断层扫描血管造影（血管OCT）上，病变更容易被检测到，并且形态分辨率更高。在FFA上，血管的功能完整性得到了更好的描绘。RFI和血管OCT是用于血管状况成像的非侵入性快速有效方法，具有易于重复性和可忽略不计的不良反应。
