Landa Gennady, Rosen Richard B
Department of Ophthalmology, New York Eye and Ear Infirmary, 310 East 14th Street, New York, NY 10003, USA.
Ophthalmic Surg Lasers Imaging. 2010 Jul-Aug;41(4):413-7. doi: 10.3928/15428877-20100325-04.
The Retinal Function Imager (RFI) (Optical Imaging, Rehovot, Israel) is a novel method for assessing retinal blood flow characteristics and demonstrating the dynamics of fine retinal vasculature. The authors report a new pattern of retinal blood flow in five patients with idiopathic juxtafoveal telangiectasia (IJT) type 2.
Retinal circulation is imaged using the RFI as a series of high-speed stroboscopically captured fundus photographs. Proprietary software aligns the images, allowing serial subtraction, and creates short video loops that show movement of red blood cells in the small and medium size retinal blood vessels.
Ten eyes of five patients with IJT type 2 were examined. In all cases, the RFI demonstrated a common pattern of centripetal vascular flow in the region of telangiectasia. This pattern is unique in its configuration of vascular flow into the focus of the area of telangiectasia. This pattern could not be appreciated on fluorescein angiography.
The RFI can detect the specific vascular pattern of the retinal blood flow in eyes of patients with IJT. The ability to characterize such blood flow patterns may aid in identification of ambiguous cases of IJT when the diagnosis is not straightforward.
视网膜功能成像仪(RFI)(以色列雷霍沃特光学成像公司)是一种评估视网膜血流特征并展示视网膜微血管系统动态的新方法。作者报告了5例2型特发性黄斑旁毛细血管扩张症(IJT)患者的一种新的视网膜血流模式。
使用RFI对视网膜循环进行成像,获取一系列通过频闪高速拍摄的眼底照片。专用软件对图像进行对齐,允许进行系列减法运算,并创建显示中小尺寸视网膜血管中红细胞运动的短视频循环。
对5例2型IJT患者的10只眼睛进行了检查。在所有病例中,RFI在毛细血管扩张区域均显示出向心性血管血流的常见模式。这种模式在血管血流向毛细血管扩张区域中心汇聚的形态上是独特的。荧光素血管造影无法观察到这种模式。
RFI能够检测IJT患者眼部视网膜血流的特定血管模式。对这种血流模式进行特征描述的能力可能有助于在诊断不明确时识别IJT的疑难病例。