Department of Chemical Engineering and Analytical Chemistry, University of Barcelona. Martí i Franquès 1-11, E08028 Barcelona, Spain.
Institut de Recerca de l'Aigua (IdRA), University of Barcelona, E08028 Barcelona, Spain.
Sensors (Basel). 2019 Sep 19;19(18):4039. doi: 10.3390/s19184039.
Carbon screen-printed electrode (SPCE), multi-walled carbon nanotubes modified screen-printed electrode (SPCNTE), carbon nanofibers modified screen-printed electrode (SPCNFE), and graphene modified screen-printed electrode (SPGPHE) were in a pioneer way tested as sensors for the simultaneous determination of the two most consumed pain-killers, paracetamol (PA) and ibuprofen (IB), and the stimulant caffeine (CF) in water by differential pulse voltammetry (DPV). Their analytical performances were compared, and the resulting sensitivities (2.50, 0.074, and 0.24 μA V mg L for PA, IB, and CF, respectively), detection limits (0.03, 0.6, and 0.05 mg L for PA, IB, and CF, respectively) and quantification limits (0.09, 2.2, and 0.2 mg L for PA, IB, and CF, respectively) suggested that the SPCNFE was the most suitable carbon-based electrode for the voltammetric determination of the selected analytes in water at trace levels. The methodology was validated using both spiked tap water and hospital wastewater samples. The results were compared to those achieved by liquid chromatography-tandem mass spectrometry (LC-MS/MS), the technique of choice for the determination of the target analytes.
碳丝网印刷电极 (SPCE)、多壁碳纳米管修饰的丝网印刷电极 (SPCNTE)、碳纳米纤维修饰的丝网印刷电极 (SPCNFE) 和石墨烯修饰的丝网印刷电极 (SPGPHE) 被首次尝试用作传感器，通过差分脉冲伏安法 (DPV) 同时测定水中两种最常消耗的止痛药对乙酰氨基酚 (PA) 和布洛芬 (IB) 以及兴奋剂咖啡因 (CF)。比较了它们的分析性能，得到的灵敏度（PA、IB 和 CF 的灵敏度分别为 2.50、0.074 和 0.24 μA V mg L）、检测限（PA、IB 和 CF 的检测限分别为 0.03、0.6 和 0.05 mg L）和定量限（PA、IB 和 CF 的定量限分别为 0.09、2.2 和 0.2 mg L）表明，SPCNFE 是最适合用于痕量水平水中所选分析物伏安测定的基于碳的电极。该方法使用加标自来水和医院废水样品进行了验证。将结果与液相色谱-串联质谱法 (LC-MS/MS) 的结果进行了比较，LC-MS/MS 是测定目标分析物的首选技术。
