Jeong Heonuk, Asai Jungo, Ushida Takashi, Furukawa Katsuko S
Department of Bioengineering, University of Tokyo, Hongo 7-3-1, Tokyo 113-8654, Japan.
Department of Mechanical Engineering, University of Tokyo, Hongo 7-3-1, Tokyo 113-8654, Japan.
Bioengineering (Basel). 2019 Sep 19;6(3):86. doi: 10.3390/bioengineering6030086.
The microstructural changes of bones, which form a hierarchy of skeletal tissue, vary, depending on their condition, and are affected by the behaviors of bone cells. The purpose of this study is to assess the microstructural changes in the inner femoral surface of Sprague Dawley rats according to the conditions using a scanning electron microscope. Microstructural differences on the endocortical surface were observed in the characteristics of osteocytic canaliculi, bone fibers, and surface roughness, showing a rougher surface in old adults and an osteoporosis model by quantitative comparison. These results could be helpful for developing a basic understanding of the microstructural changes that occur on the bone surface under various conditions.
构成骨骼组织层次结构的骨骼微观结构变化因骨骼状况而异，并受骨细胞行为的影响。本研究的目的是使用扫描电子显微镜根据不同条件评估斯普拉格-道利大鼠股骨内表面的微观结构变化。在内皮质表面观察到骨细胞小管、骨纤维和表面粗糙度特征的微观结构差异，通过定量比较显示老年大鼠和骨质疏松模型的表面更粗糙。这些结果有助于对在各种条件下骨表面发生的微观结构变化形成基本认识。
