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早期声门型喉癌放疗与声带切除术的嗓音质量评估。

Voice Quality After Radiotherapy and Cordectomy in Early-Stage Glottic Carcinomas.

机构信息

Department of Otorhinolaryngology, University of Health Sciences-Samsun Health Practices and Research Center, Samsun, Turkey.

Department of Radiation Oncology, University of Health Sciences-Samsun Health Practices and Research Center, Samsun, Turkey.

出版信息

Ear Nose Throat J. 2021 May;100(4):NP173-NP176. doi: 10.1177/0145561319876905. Epub 2019 Sep 23.

Abstract

Laryngeal carcinomas are the most common upper respiratory tract cancers and most commonly involve the glottic region. The aim of this study is to evaluate the voice quality after radiotherapy (RT) and microsurgical cordectomy (MC) treatments using Voice Handicap Index (VHI) and Grade, Roughness, Breathiness, Astenicity, and Strain (GRBAS) perceptual evaluation scale in patients with early-stage glottic carcinoma. A total of 37 patients with early-stage glottic carcinomas, 19 patients had RT and 18 patients with MC, were included in our study. The patients were evaluated in terms of their sound quality by using VHI-10 and GRBAS perceptual assessment scale 3 months after the treatment was completed. Although the findings were better in favor of RT according to GRBAS perceptual assessment scale of patients who received RT (n = 19) and MC (n = 18), no statistically significant difference was found between the 2 groups ( = .613). Patients in both groups were evaluated with VHI-10, emotional ( = .036) and physiological ( = .038) scores were significantly higher in MC group and no significant difference was found in functional scores ( = .192). However, there was no statistically significant difference between the 2 groups in terms of voice quality ( = .185). In early-stage (Tis, T1a, T1b) glottic carcinoma, there was no significant difference between RT and MC in terms of voice quality. Therefore, the choice of treatment modality in patients with early-stage glottic carcinoma should be taken into account in terms of the patient's occupation, comorbid diseases, cost of treatment, hospital stay, and, most importantly, patient preference.

摘要

喉癌是最常见的上呼吸道癌症,最常累及声门区。本研究旨在通过嗓音障碍指数(VHI)和嗓音障碍程度评估(GRBAS)量表评估早期声门型喉癌患者放射治疗(RT)和显微声带切除术(MC)治疗后的嗓音质量。共纳入 37 例早期声门型喉癌患者,其中 19 例行 RT,18 例行 MC。治疗结束后 3 个月,采用 VHI-10 和 GRBAS 感知评估量表评估患者的嗓音质量。虽然根据接受 RT(n=19)和 MC(n=18)的患者的 GRBAS 感知评估量表,RT 组的结果更好,但两组间无统计学差异(=0.613)。两组患者均采用 VHI-10 评估,MC 组的情感(=0.036)和生理(=0.038)评分显著高于 RT 组,而功能评分无显著差异(=0.192)。然而,两组间嗓音质量无统计学差异(=0.185)。在早期(Tis、T1a、T1b)声门型喉癌中,RT 和 MC 治疗在嗓音质量方面无显著差异。因此,在选择早期声门型喉癌患者的治疗方式时,应考虑患者的职业、合并症、治疗费用、住院时间,最重要的是患者的偏好。

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