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迈向新型麻风病和结核病疫苗。

Towards new leprosy and tuberculosis vaccines.

作者信息

Kaufmann S

机构信息

Abteilung Medizinische Mikrobiologie und Immunology, Oberer Eselsberg, Ulm, FRG.

出版信息

Microbiol Sci. 1987 Nov;4(11):324-8.

PMID:3155274
Abstract

Leprosy and tuberculosis are chronic infectious diseases causing major global health problems, for which no effective control by vaccination has been achieved. Recent advances in biotechnology may facilitate the design of a new vaccine generation. In this paper the need for, and the potential of, leprosy and tuberculosis vaccines are discussed.

摘要

麻风病和结核病是引起全球重大健康问题的慢性传染病，目前尚未通过疫苗接种实现有效防控。生物技术的最新进展可能有助于新一代疫苗的设计。本文讨论了麻风病和结核病疫苗的必要性及潜力。

相似文献

1
Towards new leprosy and tuberculosis vaccines.迈向新型麻风病和结核病疫苗。
Microbiol Sci. 1987 Nov;4(11):324-8.
2
Leprosy and tuberculosis vaccine design.麻风病与结核病疫苗设计。
Trop Med Parasitol. 1989 Sep;40(3):251-7.
3
[Eradication of leprosy and public health. Vaccination and multidrug therapy].[麻风病的根除与公共卫生。疫苗接种与联合化疗]
Przegl Epidemiol. 2002;56(4):577-86.
4
Vaccines against leprosy.抗麻风病疫苗
Indian J Lepr. 1991 Jul-Dec;63(3-4):342-9.
5
Towards development of a vaccine against leprosy. Introduction.迈向麻风病疫苗的研发。引言。
Lepr India. 1978 Oct;50(4):492-7.
6
Epidemiological considerations in vaccine trials in leprosy.麻风病疫苗试验中的流行病学考量
Int J Lepr Other Mycobact Dis. 1983 Dec;51(4):556-8.
7
Vaccines against leprosy.抗麻风病疫苗。
Adv Biotechnol Processes. 1990;13:201-22.
8
[The importance of the protein antigens of Mycobacterium leprae. Their potential use for the development of a vaccine against leprosy].[麻风分枝杆菌蛋白质抗原的重要性。它们在开发麻风病疫苗方面的潜在用途]
Gac Med Mex. 1991 Jan-Feb;127(1):31-9.
9
Concluding comments on development of a vaccine against leprosy.关于麻风病疫苗研发的总结评论。
Lepr India. 1978 Oct;50(4):597-8.
10
Development of an anti-leprosy vaccine -- progress in Dharmendra.一种抗麻风病疫苗的研发——在达曼德拉取得的进展。
Lepr India. 1978 Oct;50(4):488-91.

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Expression of interferon-gamma and tumour necrosis factor-alpha messenger RNA does not correlate with protection in guinea pigs challenged with virulent Mycobacterium tuberculosis by the respiratory route.呼吸道感染强毒结核分枝杆菌的豚鼠，干扰素-γ和肿瘤坏死因子-α信使 RNA 的表达与保护无关。
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Infect Immun. 2006 Jan;74(1):213-24. doi: 10.1128/IAI.74.1.213-224.2006.
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Differential expression of gamma interferon mRNA induced by attenuated and virulent Mycobacterium tuberculosis in guinea pig cells after Mycobacterium bovis BCG vaccination.卡介苗接种后豚鼠细胞中减毒和强毒结核分枝杆菌诱导的γ干扰素mRNA的差异表达
Infect Immun. 2003 Jan;71(1):354-64. doi: 10.1128/IAI.71.1.354-364.2003.
5
Effect of Mycobacterium bovis BCG vaccination on interleukin-1 beta and RANTES mRNA expression in guinea pig cells exposed to attenuated and virulent mycobacteria.牛分枝杆菌卡介苗接种对暴露于减毒和有毒力分枝杆菌的豚鼠细胞中白细胞介素-1β和RANTES mRNA表达的影响。
Infect Immun. 2002 Mar;70(3):1245-53. doi: 10.1128/IAI.70.3.1245-1253.2002.
6
The role of T cell--macrophage interactions in tuberculosis.T细胞与巨噬细胞相互作用在结核病中的作用。
Springer Semin Immunopathol. 1988;10(4):337-58. doi: 10.1007/BF02053845.
7
Immunization against tuberculosis: what kind of vaccine?结核病免疫接种：哪种疫苗？
Infect Immun. 1988 Nov;56(11):2769-73. doi: 10.1128/iai.56.11.2769-2773.1988.
8
In vitro characterization of T cells from Mycobacterium w-vaccinated mice.来自接种卡介苗小鼠的T细胞的体外特性分析
Infect Immun. 1992 Jan;60(1):257-63. doi: 10.1128/iai.60.1.257-263.1992.
9
Induction of heat shock protein closely correlates with protection against Toxoplasma gondii infection.热休克蛋白的诱导与抗弓形虫感染的保护作用密切相关。
Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):3155-8. doi: 10.1073/pnas.89.7.3155.