Social and Behavioral Research Branch, National Human Genome Research Institute 31 Center Drive, B1B36, Bethesda, MD 20892, USA.
Department of Communication, Texas A&M University, 4234 TAMU, College Station, TX 77843-4234, USA.
Per Med. 2019 Sep;16(5):387-397. doi: 10.2217/pme-2018-0148. Epub 2019 Sep 25.
This report explores the process of weight-related genomic information provision considering patient race as an important potential moderator of patient response. Health beliefs and perceived stigma were assessed following provision of genomic (versus behavioral) information by a virtual reality-based physician using either a supportive or directive communication style. Participants included 168 women with overweight. Genomic explanations, combined with supportive communication, resulted in some improved health behavior-related and interpersonal outcomes for white patients, but not black participants. Black participants, on average, did not have diminished outcomes when provided with genomic information. Genomic communications may elicit more positive interpersonal responses than behavioral explanations among both majority and minority populations, but these effects may be moderated by patient race.
本报告探讨了与体重相关的基因组信息提供过程，考虑到患者的种族是患者反应的一个重要潜在调节因素。在一位虚拟医生使用支持性或指令性沟通方式提供基因组（与行为）信息后，评估了健康信念和感知耻辱感。参与者包括 168 名超重女性。基因组解释，结合支持性沟通，导致白人患者的一些与健康行为相关的和人际方面的结果得到改善，但黑人参与者则没有。黑人参与者在提供基因组信息时，平均结果并没有恶化。基因组沟通可能会引发比行为解释更积极的人际反应，无论在多数族裔还是少数族裔中，但这些影响可能会受到患者种族的调节。
