发热出疹性疾病患儿冠状动脉扩张，无川崎病标准。
Coronary Artery Dilation in Children with Febrile Exanthematous Illness without Criteria for Kawasaki Disease.
机构信息
Hospital Central Sur de Alta Especialidad - Pediatria, Ciudad de México - México.
Hospital Central Sur Pemex - Pediatria, Ciudad de México - México.
出版信息
Arq Bras Cardiol. 2019 Dec;113(6):1114-1118. doi: 10.5935/abc.20190191.
BACKGROUND
Coronary dilatation is the most important complication of Kawasaki disease (KD) and, in addition to some clinical characteristics, is common to KD and febrile exanthematous illnesses (FEIs).
OBJECTIVE
To assess whether children with FEI, who do not meet the criteria for KD, have changes in coronary arteries dimensions.
METHODS
Echocardiography was performed within the first two weeks of the disease in patients < 10 years with fever and exanthema without other KD criteria. To make a comparison with KD patients, we reviewed the echocardiograms and medical records of patients with a diagnosis of KD of the last five years. Coronary ectasia was assessed using Z scores of coronary arteries. The means of the dimensions of the coronary arteries were compared with a z test and a level of significance of 0.05 was adopted.
RESULTS
A total of 34 patients were included, 22 (64.7%) with FEI, and 12(35.2%) with a diagnosis of KD. Using the Z scores of coronary artery, a dilation of any of the coronary artery branches was observed in six (27.2%) patients with FEI.
CONCLUSIONS
An important percentage of patients with FEI has coronary artery dilation.
背景
冠状动脉扩张是川崎病（KD）最重要的并发症，除了一些临床特征外，它也是 KD 和发热出疹性疾病（FEI）的共同特征。
目的
评估不符合 KD 标准的 FEI 患儿的冠状动脉直径是否发生变化。
方法
对发热和出疹但无其他 KD 标准的<10 岁患者在疾病的前两周内进行超声心动图检查。为了与 KD 患者进行比较，我们回顾了过去五年诊断为 KD 的患者的超声心动图和病历。使用冠状动脉的 Z 评分评估冠状动脉扩张。采用 z 检验比较冠状动脉直径的均值，采用 0.05 的显著性水平。
结果
共纳入 34 例患者，其中 22 例（64.7%）为 FEI，12 例（35.2%）诊断为 KD。使用冠状动脉 Z 评分，在 6 例（27.2%）FEI 患者中观察到任何一支冠状动脉分支扩张。
结论
FEI 患者中有相当比例的患者存在冠状动脉扩张。
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