Mujtaba Bilal, Taher Ahmed, Fiala Matthew J, Nassar Sameh, Madewell John E, Hanafy Abdelrahman K, Aslam Rizwan
Department of Diagnostic Imaging, University of Texas MD Anderson Cancer Center, Houston, USA.
The University of Texas Health Science Center at Houston, Houston USA.
Radiol Oncol. 2019 Sep 24;53(3):275-284. doi: 10.2478/raon-2019-0039.
Background Heterotopic Ossification (HO) is a common condition referring to ectopic bone formation in soft tissues. It has two major etiologies, acquired (more common) and genetic. The acquired form is closely related to tissue trauma. The exact pathogenesis of this disease remains unclear; however, there is ongoing research in prophylactic and therapeutic treatments that is promising. Conclusions Due to HO potential to cause disability, it is so important to differentiate it from other causes in order to establish the best possible management.
背景 异位骨化（HO）是一种常见病症，指的是软组织中异位骨的形成。它有两种主要病因，后天性（更常见）和遗传性。后天性形式与组织创伤密切相关。该疾病的确切发病机制仍不清楚；然而，目前在预防性和治疗性治疗方面的研究很有前景。结论 由于HO有导致残疾的可能性，为了制定最佳治疗方案，将其与其他病因区分开来非常重要。
