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常见Gm*-Am*单倍型和Km*等位基因在突尼斯人群特征描述中的进一步贡献。

Further contribution of common Gm*-Am* haplotypes and Km* alleles in the characterization of the Tunisian population.

作者信息

Helal A N, Rivat-Peran L, Van Loghem E, de Lange G, Langaney A, Lefranc G

机构信息

Faculté de Pharmacie, Monastir, Tunisie.

出版信息

Exp Clin Immunogenet. 1988;5(1):1-14.

PMID:3155402
Abstract

The Gm, Am and Km allotypes have been investigated in 405 sera from unrelated students and blood donors coming from the different areas of Tunisia. Thirty Gm and fourty-seven Gm-A2m common phenotypes have been observed. Eleven Gm* and seventeen Gm*-A2m* common haplotypes have been deduced from these phenotypes. The Tunisian population appears as mainly Caucasoid (combined frequency of Caucasoid Gm*-Am* haplotypes in the order of 0.81-0.82) with a relatively important Black contribution in the gene pool (combined frequency of Negroid Gm*-Am* haplotypes of 0.17-0.18) and a very low Oriental participation (0.01-0.02). Our results are compared to those previously reported for two other samples of the Tunisian population, the first from the regions of Mahdia and Sfax and the second from several villages of Berbers, the first inhabitants of Tunisia. Likewise, other comparisons are made with populations from Africa, Europe and Asia, since Tunisians are a mixture of Berbers, invaders and immigrants from different origins.

摘要

对来自突尼斯不同地区的405名无关学生和献血者的血清进行了Gm、Am和Km同种异型研究。观察到30种Gm和47种Gm-A2m常见表型。从这些表型中推断出11种Gm和17种Gm-A2m常见单倍型。突尼斯人群主要表现为高加索人种(高加索人种Gm-Am单倍型的合并频率约为0.81 - 0.82),基因库中有相对重要的黑人贡献(黑人Gm-Am*单倍型的合并频率为0.17 - 0.18),而东方人的参与度非常低(0.01 - 0.02)。我们的结果与之前报道的另外两个突尼斯人群样本进行了比较,第一个样本来自马赫迪耶省和斯法克斯省地区,第二个样本来自突尼斯最早的居民柏柏尔人的几个村庄。同样,由于突尼斯人是柏柏尔人、入侵者和来自不同来源的移民的混合群体,还与非洲、欧洲和亚洲的人群进行了其他比较。

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