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埃塞俄比亚大学医院药物信息咨询的特点:一项为期两年的观察性研究。

The characteristics of drug information inquiries in an Ethiopian university hospital: A two-year observational study.

机构信息

Department of Clinical pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, P.O. Box: 196, Gondar, Ethiopia.

Department of pharmaceutics, unit of Social Pharmacy, Mekelle University, Mekelle, Ethiopia.

出版信息

Sci Rep. 2019 Sep 25;9(1):13835. doi: 10.1038/s41598-019-50204-1.

DOI:10.1038/s41598-019-50204-1
PMID:31554837
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6761201/
Abstract

The types of drug-related information request from patients and health professionals, the extent of inquiry and capability of existing drug information centers are seldom studied in Ethiopia. This study aimed to identify the types and potential areas of drug information inquiry at the Drug Information Center (DIC) of Gondar University specialized Hospital (GUSH), Ethiopia. An observational study was employed. The drug information query was collected by distributing the drug information queries in different hospital units through two batches of graduating undergraduate pharmacy students. Descriptive statistics used to describe, characterize and classify drug related queries. Binary logistic regression test was employed to identify predictor variables to type of drug information query. A total of 781 drug related queries were collected and 697 were included in the final analysis. Near to half (45.3%) of queries comes from the pharmacists followed by general practitioners (11.3%) and nurses (10.2%). Slightly greater than half of the queries (51.9%) were focused on therapeutic information. 39.6% of drug related queries related to infectious disease case scenarios, followed by cardiovascular cases in 21.3% of queries. More than half of (53.9%) and nearly one in five (19.4%) of the queries took 5 to 30 minutes and 30 minutes to 1 hour of literature searching to answer, respectively. Pharmacists (with odds ratio of 2.474(95% CI (1.373-4.458)) and patients (with odds ratio of 4.121(1.403-12.105)) ask patient-specific questions in their drug related queries higher than other group of health professionals. Pharmacists are the primary drug information users and frequent drug related information inquirers at the DIC. Most of the queries targeted therapeutic indications, adverse drug events, infectious or cardiovascular disease related requests. This is imperative that drug information services can assist the growing role of pharmacists in addressing the patient specific drug related needs.

摘要

患者和卫生专业人员提出的药物相关信息类型、现有药物信息中心的查询程度和能力在埃塞俄比亚很少得到研究。本研究旨在确定埃塞俄比亚贡德尔大学专科医院(GUSH)药物信息中心(DIC)的药物信息查询类型和潜在领域。采用观察性研究。通过向不同医院单位分发药物信息查询,由两批即将毕业的本科药学学生收集药物信息查询。采用描述性统计方法对药物相关查询进行描述、描述和分类。采用二项逻辑回归检验来确定药物信息查询类型的预测变量。共收集了 781 份与药物相关的查询,其中 697 份被纳入最终分析。近一半(45.3%)的查询来自药剂师,其次是全科医生(11.3%)和护士(10.2%)。略多于一半(51.9%)的查询集中在治疗信息上。39.6%的药物相关查询与传染病病例情景有关,其次是心血管病例,占 21.3%的查询。超过一半(53.9%)和近五分之一(19.4%)的查询分别需要 5 到 30 分钟和 30 分钟到 1 小时的文献检索来回答。药剂师(比值比为 2.474(95%置信区间为 1.373-4.458))和患者(比值比为 4.121(95%置信区间为 1.403-12.105))在其药物相关查询中提出患者特异性问题的比例高于其他卫生专业人员。药剂师是 DIC 的主要药物信息使用者和频繁的药物信息查询者。大多数查询针对治疗适应症、药物不良反应、传染病或心血管疾病相关请求。这是至关重要的,药物信息服务可以协助药剂师在满足患者特定药物相关需求方面发挥更大作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e10/6761201/77e0a2257896/41598_2019_50204_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e10/6761201/77e0a2257896/41598_2019_50204_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e10/6761201/77e0a2257896/41598_2019_50204_Fig1_HTML.jpg

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本文引用的文献

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Assessment of the Use and Status of New Drug Information Centers in a Developing Country, Ethiopia: The Case of Public University Hospital Drug Information Centers.评估发展中国家(埃塞俄比亚)新药信息中心的使用和现状:以公立大学医院药物信息中心为例。
Biomed Res Int. 2018 Aug 26;2018:3840976. doi: 10.1155/2018/3840976. eCollection 2018.
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抗菌药物管理:一项评估埃塞俄比亚社区药剂师认知与实践的横断面调查
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