Motuziuk Igor, Sydorchuk Oleg, Kostiuchenko Yevhenii, Kovtun Natalia, Poniatovskyi Petro
Oncology Department, Bogomolets National Medical University, Kyiv, Ukraine.
Statistics and Demography Department, Faculty of Economics, Taras Shevchenko National University of Kyiv, Kyiv, Ukraine.
Breast Cancer (Auckl). 2019 Sep 17;13:1178223419876931. doi: 10.1177/1178223419876931. eCollection 2019.
The aim of this study was to develop and implement the concept of fast-track surgery (FTS) for reconstructive breast surgery in patients with breast cancer (BC) to improve early and long-term results of treatment.
The study includes 749 patients with stage 1 to 3 BC. A total of 253 patients with BC got treatment according to FTS program and were included to the core group. Other 496 patients with BC (control group) were not included to the FTS program. Patients were treated from December 2010 to December 2014. All age groups were covered (18-70 years old).
There was a significant difference in the average length of hospital stay (LOS) which was 14.27 ± 7.00 days in the core group and 20.11 ± 7.70 days in the control group ( < .001). In advanced BC cases in the core group, LOS was >8 days lower comparing with the control group on average. The LOS in patients who underwent adjuvant chemotherapy was 2.7 times lower in the FTS group comparing with the control group.
The study results allow us to recommend the concept of FTS for implementation in broad medical practice for breast reconstructive surgery in patients with BC. The FTS program was shown to be effective in all types of breast surgery, including immediate oncoplastic and reconstructive surgeries. The gradual reduction of LOS increased the number of surgeries in our department by 75% from 2008 till 2018.
本研究的目的是为乳腺癌（BC）患者的乳房重建手术开发并实施快速康复外科（FTS）概念，以改善治疗的早期和长期效果。
本研究纳入749例1至3期BC患者。共有253例BC患者按照FTS方案接受治疗并纳入核心组。其他496例BC患者（对照组）未纳入FTS方案。患者于2010年12月至2014年12月接受治疗。涵盖所有年龄组（18 - 70岁）。
平均住院时间（LOS）存在显著差异，核心组为14.27±7.00天，对照组为20.11±7.70天（<0.001）。在核心组的晚期BC病例中，LOS平均比对照组低8天以上。FTS组接受辅助化疗患者的LOS比对照组低2.7倍。
研究结果使我们能够推荐FTS概念在BC患者乳房重建手术的广泛医学实践中实施。FTS方案在所有类型的乳房手术中均显示有效，包括即刻肿瘤整形和重建手术。从2008年到2018年，LOS的逐渐缩短使我们科室的手术量增加了75%。
