光致变色酞菁组装纳米粒子用于控制“双重锁定”光动力疗法。
Photoswitchable phthalocyanine-assembled nanoparticles for controlled "double-lock" photodynamic therapy.
机构信息
Department of Chemistry and Nano Science Ewha Womans University, Seoul 120-750, Korea.
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
出版信息
Chem Commun (Camb). 2019 Oct 10;55(82):12316-12319. doi: 10.1039/c9cc03960k.
In the current study, a new nanoparticle platform, NanoAzoPcS, is created by co-assembly of phthalocyanine and azobenzene amphiphiles, which can be used to gain precise control of PDT simply by regulating the stoichiometric ratio of the components and using light irradiation. The results of antibacterial studies show that NanoAzoPcS serves as a smart PS for controlled PDT.
在本研究中，通过组装酞菁和偶氮苯两亲分子，构建了一种新的纳米颗粒平台 NanoAzoPcS，它可以通过调节组件的化学计量比并用光照来精确控制 PDT。抗菌研究结果表明，NanoAzoPcS 是一种用于控制 PDT 的智能 PS。
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