Rafati-Rahimzadeh Mehrdad, Rafati-Rahimzadeh Mehravar, Kazemi Sohrab, Moghadamnia Ali Akbar
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Department of Medical Physics, Kashan University of Medical Sciences, Kashan, Iran.
Caspian J Intern Med. 2019 Summer;10(3):241-264. doi: 10.22088/cjim.10.3.241.
Among the blistering (vesicant) chemical warfare agents (CWA), sulfur mustard is the most important since it is known as the "King of chemical warfare agents". The use of sulfur mustard has caused serious damages in several organs, especially the eyes, skin, respiratory, central and peripheral nervous systems after short and long term exposure, incapacitating and even killing people and troops. In this review, chemical properties, mechanism of actions and their effects on each organ, clinical manifestations, diagnostic evaluation of the actions triage, and treatment of injuries have been described.
在起泡(糜烂性)化学战剂(CWA)中,芥子气最为重要,因为它被誉为“化学战剂之王”。芥子气的使用已对多个器官造成严重损害,尤其是眼睛、皮肤、呼吸系统、中枢和周围神经系统,在短期和长期接触后,会使人和部队丧失能力甚至死亡。在这篇综述中,已描述了芥子气的化学性质、作用机制及其对各器官的影响、临床表现、行动分类的诊断评估以及损伤的治疗。