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3个月以下婴儿肛周脓肿的病原体及疗效分析

The pathogens and curative effects analysis of perianal abscess of infants under 3 months.

作者信息

Zhu Yimin, Xu Fuying

机构信息

Department of General Surgery, The First Affiliated Hospital of Lishui University, Lishui, China.

出版信息

Turk J Pediatr. 2019;61(1):40-43. doi: 10.24953/turkjped.2019.01.007.

DOI:10.24953/turkjped.2019.01.007
PMID:31559720
Abstract

Zhu Y, Xu F. The pathogens and curative effects analysis of perianal abscess of infants under 3 months. Turk J Pediatr 2019; 61: 40-43. In order to guide clinical treatment for perianal abscess of young infants, the characteristics of pathogens and curative effects analysis were conducted. Bacterial culture results, antibiotics susceptibility tests and curative effects of abscess incision were retrospectively analyzed in 66 cases of perianal abscess of infants under 3 months. There were 48 cases of Klebsiella pneumoniae, 7 cases of Staphylococcus, 6 cases of Escherichia coli, 5 cases of Proteus in the pathogen culture results. Klebsiella pneumoniae, the predominant pathogen, was susceptible to most antibiotics, especially to imipenem, cefoperazonesulbactam and amikacin with low drug resistance rates. However, high drug resistance rates were found to ampicillin and nitrofurantion. After abscess incision, the complication rate of anal fistula was 6.6% in infants under 3 months and 60.3% in the adult group. There was significant difference P<0.01. In conclusion, Klebsiella pneumoniae was the most common pathogen in perianal abscess of infants under 3 months and was commonly resistant to ampicillin and nitrofurantion. Since perianal abscess of infants under 3 months is a self-limited disorder, simple surgical intervention and synchronous sensitive antibiotic administration are suggested as the optimal management.

摘要

朱Y,徐F。3个月以下婴儿肛周脓肿的病原体及疗效分析。《土耳其儿科学杂志》2019年;61:40 - 43。为指导婴幼儿肛周脓肿的临床治疗,对其病原体特征及疗效进行分析。回顾性分析66例3个月以下婴儿肛周脓肿的细菌培养结果、抗生素药敏试验及脓肿切开的疗效。病原体培养结果中肺炎克雷伯菌48例,葡萄球菌7例,大肠埃希菌6例,变形杆菌5例。肺炎克雷伯菌作为主要病原体,对大多数抗生素敏感,尤其是对亚胺培南、头孢哌酮舒巴坦和阿米卡星耐药率较低。然而,对氨苄西林和呋喃妥因耐药率较高。脓肿切开后,3个月以下婴儿肛瘘并发症发生率为6.6%,成人组为60.3%。差异有统计学意义(P<0.01)。结论:肺炎克雷伯菌是3个月以下婴儿肛周脓肿最常见的病原体,且对氨苄西林和呋喃妥因普遍耐药。由于3个月以下婴儿肛周脓肿是一种自限性疾病,建议采用简单的手术干预并同步使用敏感抗生素作为最佳治疗方法。

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