Wildhirt E
MMW Munch Med Wochenschr. 1978 Nov 17;120(46):1541-4.
Six cases of persisting hepatitis with a duration of 3 to 9 years are reported. During this time 2--3 acute inflammatory episodes occurred with transaminase levels raised to more than 500 U/l. Icterus did not occur during these attacks. The remaining laboratory parameters which are usually normal in persisting hepatitis (gamma-GT, bromsulfalein) were pathological during the acute attack and later became normal. As the disease progressed after overcoming the attack, the transaminases were only slightly raised in all cases. Laparoscopy and histological examinations of between three and nine punctates gave an unchanged picture of chronic persisting hepatitis. During the acute attack the inflammatory activities in the liver punctates increased, there were also increased single cell necroses. It is suggested that this peculiar type of chronic persisting hepatitis shall be called "acute recurrent persistent hepatitis.".
报告了6例病程为3至9年的持续性肝炎病例。在此期间，发生了2至3次急性炎症发作，转氨酶水平升至500 U/l以上。这些发作期间未出现黄疸。在持续性肝炎中通常正常的其余实验室参数（γ-谷氨酰转移酶、酚四溴酞磺酸钠）在急性发作期间呈病理性，随后恢复正常。随着疾病在发作后进展，所有病例中转氨酶仅略有升高。对3至9个穿刺点进行的腹腔镜检查和组织学检查显示慢性持续性肝炎的情况未变。在急性发作期间，肝脏穿刺点的炎症活动增加，单细胞坏死也增多。建议将这种特殊类型的慢性持续性肝炎称为“急性复发性持续性肝炎”。
