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血管外科中3D打印技术的应用趋势:一项调查

Trends in use of 3D printing in vascular surgery: a survey.

作者信息

Marti Patrizia, Lampus Flavio, Benevento Domenico, Setacci Carlo

机构信息

Department of Social Political and Cognitive Science, University of Siena, Siena, Italy -

Department of Social Political and Cognitive Science, University of Siena, Siena, Italy.

出版信息

Int Angiol. 2019 Oct;38(5):418-424. doi: 10.23736/S0392-9590.19.04148-8. Epub 2019 Sep 20.

Abstract

INTRODUCTION

The purpose of the following research was to provide a systematic survey on the use of additive manufacturing in vascular surgery. The survey focuses on applications of 3D printing in endovascular surgery like endovascular aneurysm repair (EVAR), a quite unexplored application domain. 3D printing is an additive production process of three-dimensional objects starting from a three-dimensional digital model. This kind of manufacturing process is getting great attention in the medical field and new applications have emerged in recent years especially thanks to the combination of additive printing with 3D imaging techniques. The purpose of the study is to reflect on additive manufacturing and its potential as an inclusive manufacturing practice which can provide benefits at economic and societal level.

EVIDENCE ACQUISITION

The article first introduces the use of 3D printing in surgery by summarizing the results of previous reviews which reveal three main usages of 3D printing: anatomic models, surgical tools, implants and prostheses. These studies point out that vascular surgery is still an unexplored field of application of 3D printing. Starting from this result, a new survey was carried out in databases Pubmed, Elsevier, Research Gate and ACM Digital Library for terms related to 3D printing in vascular surgery using the following keywords: 3D printing, vascular surgery, EVAR, aneurysm. The search screened articles published up to 2019 for relevance and practical application of the technology in vascular surgery, in particular the topic is related to the treatment of complex abdominal aortic aneurysm.

EVIDENCE SYNTHESIS

Initially 437 records published up to 2019 were found, but then were narrowed down to 29 full-text articles. The findings reveal that in addition to the applications found in the previous studies, new experiments are ongoing related to the use of 3D printing in the "Off label" practice to manually fenestrate the stent to improve the accuracy of the EVAR.

CONCLUSIONS

Different applications of the use of 3D printing and digital imaging in vascular surgery have been experimented with a different maturity level. Whilst the technology has increased its potential in the latest years, the number of studies documented in the literature is still quite narrow. Further research is necessary to fully test the potential of 3D printing, also in combination with other technologies (e.g. 3D imaging and CNC cutting). Early experimentations show that these technologies have the potential to radically change the vascular surgery practice in the near future, in particular in treatment like EVAR, to improve the planning and therefore the success of the surgery.

摘要

引言

以下研究的目的是对增材制造在血管外科手术中的应用进行系统调查。该调查聚焦于3D打印在血管内手术中的应用,如血管内动脉瘤修复术(EVAR),这是一个尚未充分探索的应用领域。3D打印是一种从三维数字模型开始制造三维物体的增材制造工艺。这种制造工艺在医学领域正受到极大关注,近年来出现了许多新应用,这尤其得益于增材打印与3D成像技术的结合。本研究的目的是思考增材制造及其作为一种包容性制造实践的潜力,这种实践能够在经济和社会层面带来益处。

证据获取

本文首先通过总结先前综述的结果介绍了3D打印在手术中的应用,这些结果揭示了3D打印的三种主要用途:解剖模型、手术工具、植入物和假体。这些研究指出,血管外科手术仍是3D打印一个尚未充分探索的应用领域。基于这一结果,在数据库PubMed、爱思唯尔、Research Gate和ACM数字图书馆中开展了一项新的调查,使用以下关键词搜索与血管外科手术中3D打印相关的术语:3D打印、血管外科手术、EVAR、动脉瘤。该搜索筛选了截至2019年发表的文章,以查找该技术在血管外科手术中的相关性和实际应用,特别是该主题与复杂腹主动脉瘤的治疗相关。

证据综合

最初发现了截至2019年发表的437条记录,但随后缩小至29篇全文文章。研究结果表明,除了先前研究中发现的应用外,正在进行与3D打印在“超说明书”实践中的应用相关的新实验,即手动为支架开窗以提高EVAR的准确性。

结论

3D打印和数字成像在血管外科手术中的不同应用已在不同成熟度水平上进行了试验。尽管该技术近年来潜力有所增加,但文献中记录的研究数量仍然相当有限。有必要进行进一步研究以充分测试3D打印的潜力,也包括与其他技术(如3D成像和数控切割)相结合的情况。早期实验表明,这些技术有可能在不久的将来从根本上改变血管外科手术实践,特别是在如EVAR这样的治疗中,以改进手术规划从而提高手术成功率。

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