Department of Otorhinolaryngology, Adana City Training and Research Hospital, 01060, Adana, Turkey.
Department of Anesthesiology and Reanimation, Adana City Training and Research Hospital, Adana, Turkey.
Eur Arch Otorhinolaryngol. 2020 Jan;277(1):255-260. doi: 10.1007/s00405-019-05668-2. Epub 2019 Sep 28.
The objective of this study was to compare the efficacy of peritonsillar and glossotonsillar sulcus infiltration with bupivacaine to manage postoperative pain and odynophagia in children undergoing tonsillectomy.
Fifty children (5-10 years of age) undergoing tonsillectomy due to recurrent tonsillar infections were enrolled in the study and assigned into two groups receiving either pre-incisional peritonsillar (Group 1, n = 25) or glossotonsillar sulcus (Group 2, n = 25) infiltration with 1 mg/kg bupivacaine (0.5%) totaling 5 mL in volume. At different time intervals following arrival to the post-anesthesia care unit (PACU), the participants in each group were evaluated for pain using the modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) and for odynophagia using a four-point scale (1-none, normal or no difficulty with swallowing, 2-mild, mild difficulty with swallowing, 3-moderate, moderate difficulty with swallowing, and 4-severe, no swallowing or swallowing only with maximal effort). Additional parameters were assessed for 24 h post-surgery, including time to first administration of analgesic, additional analgesic requirements, nausea/vomiting, allergic reaction, and bleeding.
Infiltration of either region with bupivacaine yielded similar analgesic effects at different times following the surgery (P = 0.065). Time to first analgesic treatment and additional analgesic requirements were not significantly different between groups (P = 0.181). Compared to the Group 1, Group 2 was associated with significantly lower odynophagia scores at different times after the surgery (P = 0.020).
Present results indicate that the infiltration of local anesthetics to glossotonsillar sulcus is a safe, practical, and effective pain management intervention without risk of significant side effects for children undergoing tonsillectomy.
本研究旨在比较扁桃体周和舌扁桃体沟浸润布比卡因在治疗因复发性扁桃体感染而行扁桃体切除术的儿童术后疼痛和吞咽困难方面的疗效。
本研究纳入了 50 名(5-10 岁)因复发性扁桃体感染而行扁桃体切除术的儿童,并将其分为两组,分别接受扁桃体周(第 1 组,n = 25)或舌扁桃体沟(第 2 组,n = 25)浸润 1mg/kg 布比卡因(0.5%),总量为 5mL。在到达麻醉后护理单元(PACU)后的不同时间间隔,每组患者均使用改良的安大略儿童医院疼痛量表(mCHEOPS)评估疼痛,使用四点量表(1-无,正常或吞咽无困难,2-轻度,吞咽轻度困难,3-中度,吞咽中度困难,4-重度,无法吞咽或仅通过最大努力吞咽)评估吞咽困难。术后 24 小时内还评估了其他参数,包括首次使用镇痛药的时间、额外镇痛需求、恶心/呕吐、过敏反应和出血。
两种区域的布比卡因浸润在手术后的不同时间都产生了相似的镇痛效果(P = 0.065)。两组之间首次镇痛治疗时间和额外镇痛需求无显著差异(P = 0.181)。与第 1 组相比,第 2 组在手术后的不同时间点的吞咽困难评分显著较低(P = 0.020)。
目前的结果表明,在接受扁桃体切除术的儿童中,将局麻药浸润到舌扁桃体沟是一种安全、实用且有效的疼痛管理干预措施,且无明显副作用的风险。