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直肠给予对乙酰氨基酚与扁桃体周围浸润布比卡因用于儿童腺样体扁桃体切除术后镇痛。

Rectal acetaminophen versus peritonsillar infiltration of bupivacaine for postoperative analgesia after adenotonsillectomy in children.

机构信息

Anesthesiology Research Center, Shahid Beheshti University of Medicine, Tehran, Iran.

出版信息

Eur Arch Otorhinolaryngol. 2011 Apr;268(4):581-4. doi: 10.1007/s00405-010-1434-5. Epub 2010 Dec 7.

Abstract

There are a wide range of analgesic methods used for postoperative pain control in children undergoing elective adenotonsillectomy and there are many cases in which the postoperative analgesic modalities have not been fully successful to treat pain effectively. The acute postoperative analgesic effects of peritonsillar bupivacaine infiltration compared with rectal acetaminophen suppositories in elective adenotonsillectomy have been compared here. The methods employed were a single blind randomized clinical trail where 110 cases were selected to enter the study. After induction of anesthesia and intubation, and just before start of the procedure, the 1st group received 30 mg/kg of acetaminophen rectally; while, the 2nd group received 1 mg/kg peritonsillar bupivacaine infiltration around the tonsils. Throat pain at rest, after swallowing, after taking fluid and after soft food and also, parents' and nurses satisfaction regarding patient analgesia were compared. The results stated that there was no difference between the two groups regarding throat pain at rest, after swallowing, after taking fluid and after soft food and also, parents' and nurses' satisfaction. We concluded that when considering the feasibility of rectal acetaminophen, the results of the study suggest it superior due to minimal risks compared with local peritonsillar administration of bupivacaine for elective adenotonsillectomy of children.

摘要

用于儿童选择性扁桃体腺样体切除术术后疼痛控制的镇痛方法有很多种,而且很多情况下,术后镇痛方式并没有完全成功有效地治疗疼痛。本研究比较了扁桃体周围布比卡因浸润与直肠对乙酰氨基酚栓剂在选择性扁桃体腺样体切除术中的急性术后镇痛效果。采用单盲随机临床试验,选择 110 例患者进入研究。在麻醉诱导和插管后,在手术开始前,第 1 组给予 30mg/kg 的对乙酰氨基酚直肠给药;第 2 组给予 1mg/kg 的扁桃体周围布比卡因浸润。比较两组患者在静息、吞咽、饮水、进食软食时的咽喉痛以及家长和护士对患者镇痛的满意度。结果表明,两组患者在静息、吞咽、饮水和进食软食时的咽喉痛以及家长和护士的满意度方面无差异。我们得出结论,考虑到直肠对乙酰氨基酚的可行性,研究结果表明,与局部扁桃体周围布比卡因给药相比,其具有更小的风险,因此对于儿童选择性扁桃体腺样体切除术更为优越。

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