Coppeto J R, Yamase H, Monteiro M L
J Clin Neuroophthalmol. 1985 Mar;5(1):17-25.
A case of Wegener's granulomatosis is reported which manifested episcleritis followed by scleritis, and followed in turn by separate episodes of right and left orbital pseudotumor spanning 15 years prior to respiratory tract disease. The unusually protracted progression of symptoms in this case may be explained on the basis of the histopathological findings. Areas of fibrinoid necrosis of connective tissue occurred alone or alternated with areas of nongranulomatous fibrinoid necrosis of blood vessel walls. Granulomatours vasculitis was not observed. This histopathological picture is pathognomic of early cases of Wegener's granulomatosis which run especially protracted courses.
报告了1例韦格纳肉芽肿病，其表现为先是巩膜外层炎，接着是巩膜炎，随后在呼吸道疾病出现前的15年里先后出现右侧和左侧眼眶假瘤。该病例症状异常迁延的进展情况可根据组织病理学发现来解释。结缔组织的纤维蛋白样坏死区域单独出现或与血管壁的非肉芽肿性纤维蛋白样坏死区域交替出现。未观察到肉芽肿性血管炎。这种组织病理学表现是病程特别迁延的早期韦格纳肉芽肿病病例的特征性表现。
