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种族与民族因素对小儿患者行区域麻醉的影响:25664 例手术中的 3189 例区域麻醉的单中心研究。

Association Between Race and Ethnicity in the Delivery of Regional Anesthesia for Pediatric Patients: A Single-Center Study of 3189 Regional Anesthetics in 25,664 Surgeries.

机构信息

From the Department of Pediatric Anesthesiology, Ann and Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California.

出版信息

Anesth Analg. 2020 Jul;131(1):255-262. doi: 10.1213/ANE.0000000000004456.

Abstract

BACKGROUND

Racial and ethnic disparities in health care are well documented in the United States, although evidence of disparities in pediatric anesthesia is limited. We sought to determine whether there is an association between race and ethnicity and the use of intraoperative regional anesthesia at a single academic children's hospital.

METHODS

We performed a retrospective review of all anesthetics at an academic tertiary children's hospital between May 4, 2014, and May 31, 2018. The primary outcome was delivery of regional anesthesia, defined as a neuraxial or peripheral nerve block. The association between patient race and ethnicity (white non-Hispanic or minority) and receipt of regional anesthesia was assessed using multivariable logistic regression. Sensitivity analyses were performed comparing white non-Hispanic to an expansion of the single minority group to individual racial and ethnic groups and on patients undergoing surgeries most likely to receive regional anesthesia (orthopedic and urology patients).

RESULTS

Of 33,713 patient cases eligible for inclusion, 25,664 met criteria for analysis. Three-thousand one-hundred eighty-nine patients (12.4%) received regional anesthesia. One thousand eighty-six of 8884 (13.3%) white non-Hispanic patients and 2003 of 16,780 (11.9%) minority patients received regional anesthesia. After multivariable adjustment for confounding, race and ethnicity were not found to be significantly associated with receiving intraoperative regional anesthesia (adjusted odds ratios [ORs] = 0.95; 95% confidence interval [CI], 0.86-1.06; P = .36). Sensitivity analyses did not find significant differences between the white non-Hispanic group and individual races and ethnicities, nor did they find significant differences when analyzing only orthopedic and urology patients, despite observing some meaningful clinical differences.

CONCLUSIONS

In an analysis of patients undergoing surgical anesthesia at a single academic children's hospital, race and ethnicity were not significantly associated with the adjusted ORs of receiving intraoperative regional anesthesia. This finding contrasts with much of the existing health care disparities literature and warrants further study with additional datasets to understand the mechanisms involved.

摘要

背景

在美国,医疗保健中的种族和民族差异得到了充分的记录,尽管小儿麻醉方面的差异证据有限。我们试图确定在一家学术性儿童医院,种族和民族与术中区域麻醉的使用之间是否存在关联。

方法

我们对 2014 年 5 月 4 日至 2018 年 5 月 31 日期间在一家学术性三级儿童医院进行的所有麻醉进行了回顾性分析。主要结局是给予区域麻醉,定义为神经轴或周围神经阻滞。使用多变量逻辑回归评估患者种族和民族(白种非西班牙裔或少数族裔)与接受区域麻醉之间的关联。进行了敏感性分析,将白种非西班牙裔与单一少数族裔群体扩展为个体种族和族裔群体进行比较,并对最有可能接受区域麻醉的手术患者(骨科和泌尿科患者)进行了比较。

结果

在 33713 例符合纳入标准的患者中,有 25664 例符合分析标准。3189 例患者(12.4%)接受了区域麻醉。在 8884 例白种非西班牙裔患者中,有 1086 例(13.3%)和 16780 例少数族裔患者中的 2003 例(11.9%)接受了区域麻醉。在调整混杂因素后,种族和民族与接受术中区域麻醉之间没有发现显著关联(调整后的优势比[OR] = 0.95;95%置信区间[CI],0.86-1.06;P =.36)。敏感性分析未发现白种非西班牙裔组与个体种族和族裔之间存在显著差异,也未发现仅分析骨科和泌尿科患者时存在显著差异,尽管观察到一些有意义的临床差异。

结论

在对一家学术性儿童医院接受手术麻醉的患者进行分析时,种族和民族与接受术中区域麻醉的调整后 OR 之间没有显著关联。这一发现与大多数现有的医疗保健差异文献形成对比,需要进一步研究,并结合其他数据集来了解所涉及的机制。

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