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慢性尾骨痛的阴部神经节阻滞治疗中是否需要使用类固醇?一项前瞻性双盲临床试验。

Are steroids required in the treatment of ganglion impar blockade in chronic coccydynia? a prospective double-blinded clinical trial.

作者信息

Sencan Savas, Edipoglu Ipek Saadet, Ulku Demir Fatma Gul, Yolcu Gunay, Gunduz Osman Hakan

机构信息

Division of Pain Medicine, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Marmara University, Istanbul, Turkey.

Department of Physical Medicine and Rehabilitation, Kayseri City Hospital, Kayseri, Turkey.

出版信息

Korean J Pain. 2019 Oct 1;32(4):301-306. doi: 10.3344/kjp.2019.32.4.301.

Abstract

BACKGROUND

Ganglion impar blockade is a reliable and effective treatment option used in patients with coccydynia. Our primary objective was to specify the role of corticosteroids in impar blockade. We compared applications of local anesthetic with the local anesthetic + corticosteroid combination in terms of treatment efficiency in patients with chronic coccydynia.

METHODS

Our study was a prospective randomize double-blind study. The patients were divided into 2 groups after randomization. The first group (group SL) was made up of patients where a corticosteroid + local anesthetic were used during ganglion impar blockade. In the second group (group L) we used only local anesthetic. We evaluated numeric rating scale (NRS) and Beck depression scale, which were employed before the procedure and in 1st and 3rd months after the procedure.

RESULTS

Seventy-three patients were included in the final analysis. We detected a significantly greater decrease in NRS values in the 1st month in group SL than in group L ( = 0.001). In the same way, NRS values in the 3rd month were significantly lower in the group with steroids ( = 0.0001). During the evaluation of the Beck test, we detected significantly greater decreases in the 1st month ( = 0.017) and 3rd month ( = 0.021) in the SL group than in the L group.

CONCLUSIONS

Ganglion impar blockade decreases pain in the treatment of chronic coccydynia and improve depression. Addition of steroids in a ganglion impar blockade is required for treatment response that should accumulate over a long period of time.

摘要

背景

奇神经节阻滞是用于尾骨痛患者的一种可靠且有效的治疗选择。我们的主要目的是明确皮质类固醇在奇神经节阻滞中的作用。我们比较了局部麻醉剂与局部麻醉剂加皮质类固醇联合应用对慢性尾骨痛患者的治疗效果。

方法

我们的研究是一项前瞻性随机双盲研究。患者随机分组后分为两组。第一组(SL组)由在奇神经节阻滞时使用皮质类固醇加局部麻醉剂的患者组成。第二组(L组)仅使用局部麻醉剂。我们评估了数字评分量表(NRS)和贝克抑郁量表,在手术前以及术后第1个月和第3个月使用。

结果

73例患者纳入最终分析。我们发现SL组在第1个月时NRS值的下降幅度明显大于L组(P = 0.001)。同样,使用类固醇的组在第3个月时NRS值明显更低(P = 0.0001)。在评估贝克测试时,我们发现SL组在第1个月(P = 0.017)和第3个月(P = 0.021)的下降幅度明显大于L组。

结论

奇神经节阻滞在慢性尾骨痛治疗中可减轻疼痛并改善抑郁。在奇神经节阻滞中添加类固醇对于需要长期积累的治疗反应是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbb0/6813902/6c0c7ac20c08/KJP-32-301-g001.jpg

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