利用光学相干断层扫描技术在甲状腺和甲状旁腺手术中快速识别头颈部组织。
Rapid head and neck tissue identification in thyroid and parathyroid surgery using optical coherence tomography.
机构信息
Centre Hospitalier de l'Université de Montréal, Department of Otolaryngology-Head & Neck Surgery, Montreal, Quebec, Canada.
Department of Engineering Physics, École Polytechnique de Montréal, Montreal, Quebec, Canada.
出版信息
Head Neck. 2019 Dec;41(12):4171-4180. doi: 10.1002/hed.25972. Epub 2019 Oct 1.
BACKGROUND
Optical coherence tomography (OCT) is a noninvasive imaging modality that may reproduce the microarchitecture of tissues in real-time. This study examines whether OCT can render distinct images of thyroid, parathyroid glands, adipose tissue, and lymph nodes in both healthy and pathological states.
METHODS
Twenty-seven patients undergoing thyroidectomy, parathyroidectomy, and/or neck dissection for thyroid cancer were recruited prospectively for imaging prior to histopathological analysis.
RESULTS
Based on 122 imaged specimens, qualitative OCT descriptions were derived for healthy thyroid, parathyroid gland, adipose tissue, and lymph node. The frequencies at which distinguishing features were present for each tissue type were 88%, 83%, 100%, and 82%. OCT appearance of pathological specimens were also described.
CONCLUSIONS
Healthy neck tissues have distinct OCT appearances, which could facilitate parathyroid identification during thyroidectomies. However, images of parathyroid adenomas could be confused with those of lymph nodes, and benign and malignant thyroid nodules could not be differentiated.
背景
光学相干断层扫描（OCT）是一种非侵入性的成像方式，可以实时再现组织的微观结构。本研究旨在探讨 OCT 是否能在健康和病理状态下对甲状腺、甲状旁腺、脂肪组织和淋巴结进行清晰成像。
方法
前瞻性地招募了 27 名因甲状腺癌行甲状腺切除术、甲状旁腺切除术和/或颈部淋巴结清扫术的患者，在进行组织病理学分析之前进行成像。
结果
根据 122 个成像标本，得出了健康甲状腺、甲状旁腺、脂肪组织和淋巴结的 OCT 定性描述。每种组织类型的鉴别特征出现的频率分别为 88%、83%、100%和 82%。还描述了病理性标本的 OCT 表现。
结论
健康颈部组织具有独特的 OCT 表现，有助于在甲状腺切除术中识别甲状旁腺。然而，甲状旁腺腺瘤的图像可能与淋巴结的图像混淆，且良性和恶性甲状腺结节无法区分。
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