Dominguez Jacqueline Cotoong, Phung Thien Kieu Thi, de Guzman Ma Fe Payno, Fowler Krizelle Cleo, Reandelar Macario, Natividad Boots, Waldemar Gunhild, Nielsen Thomas Rune, Pamintuan Aquial Mary Rose, Holandez Rachelle Layda, Ligsay Antonio Disederio
Institute for Neurosciences, St. Luke's Medical Center, Quezon City, Philippines.
Danish Dementia Research Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Dement Geriatr Cogn Dis Extra. 2019 Aug 13;9(2):260-270. doi: 10.1159/000500519. eCollection 2019 May-Aug.
Filipino normative data for neuropsychological tests are lacking.
This study aimed to determine the Filipino normative data for the Filipino Norming Project (FNP) Neuropsychological Battery, combining the Alzheimer's Disease Assessment Scale - Cognitive (ADAS-Cog) and the Neuropsychological Test Battery from the Uniform Dataset of Alzheimer's Disease Center (UDS-ADC).
We recruited participants 60 years and older with normal cognition (MMSE score of 25 and above and did not fulfill criteria for dementia according to DSM-IV criteria). Psychologists administered the tests to the study participants. We conducted multivariate analyses to study the effect of age, gender, and education on test performance.
A total of 191 participants underwent the FNP Neuropsychological Test Battery. The mean age was 68.8 years (SD 5.4). The majority were female (84.1%). The mean score of ADAS-Cog was 9.98 (SD 4.74). The effect of education was prominent throughout the cognitive domains tested while the effect of age was limited to a few cognitive domains. The mean ADAS-Cog scores were 11.80 ± 4.40 for primary education, 9.93 ± 5.08 for secondary, and 8.15 ± 3.95 for tertiary. On average, women scored 2.75 points lower than men and performed better on the verbal components. Men performed better on the constructional praxis component. The same effect of education and gender was observed for the UDS-ADC.
For the first time, normative data are available for the ADAS-Cog and UDS-ADC for a Filipino older population. This study stresses the importance of establishing population-specific normative data, taking into account the specific sociocultural and linguistic context of that population.
缺乏菲律宾人神经心理学测试的常模数据。
本研究旨在确定菲律宾常模项目(FNP)神经心理测验组合的菲律宾常模数据,该测验组合结合了阿尔茨海默病评估量表 - 认知部分(ADAS - Cog)和阿尔茨海默病中心统一数据集(UDS - ADC)的神经心理测验组合。
我们招募了60岁及以上认知正常的参与者(简易精神状态检查表[MMSE]得分25分及以上,且不符合DSM - IV标准的痴呆症标准)。心理学家对研究参与者进行测试。我们进行多变量分析以研究年龄、性别和教育程度对测试表现的影响。
共有191名参与者接受了FNP神经心理测验组合测试。平均年龄为68.8岁(标准差5.4)。大多数为女性(84.1%)。ADAS - Cog的平均得分为9.98(标准差4.74)。在所有测试的认知领域中,教育程度的影响都很显著,而年龄的影响仅限于少数认知领域。小学教育程度者的ADAS - Cog平均得分为11.80±4.40,中学教育程度者为9.93±5.08,高等教育程度者为8.15±3.95。平均而言,女性得分比男性低2.75分,在语言部分表现更好。男性在构建实践部分表现更好。在UDS - ADC中也观察到了相同的教育程度和性别的影响。
首次获得了菲律宾老年人群体ADAS - Cog和UDS - ADC的常模数据。本研究强调了建立针对特定人群的常模数据的重要性,同时要考虑到该人群特定的社会文化和语言背景。