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1例伴有染色体畸变(49, XX, +3, +i(6)(p10), +mar)的肺黏膜相关淋巴组织淋巴瘤。

A case of a pulmonary mucosa-associated lymphoid tissue lymphoma with chromosomal aberration (49, XX, +3, +i(6)(p10), +mar).

作者信息

Ojima Toshihiro, Homma Takahiro, Shimada Yoshifumi, Kitamura Naoya, Akemoto Yushi, Yoshimura Naoki

机构信息

Department of Thoracic Surgery Kurobe City Hospital Toyama Japan.

Department of General Thoracic and Cardiovascular Surgery University of Toyama Toyama Japan.

出版信息

Respirol Case Rep. 2019 Sep 25;7(9):e00489. doi: 10.1002/rcr2.489. eCollection 2019 Dec.

Abstract

We report a case of a primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma with chromosomal aberration (49, XX, +3, +i(6)(p10), +mar). A 59-year-old woman was referred to our hospital for an abnormal chest shadow detected during a routine health check-up in 2014. Chest computed tomography revealed a 3.2- × 2.3- × 2.0-cm tumour shadow in the right middle lobe. Transbronchial biopsy did not result in the diagnosis of the tumour. Accordingly, as the tumour could have been malignant, right middle lobectomy was performed via video-assisted thoracic surgery. On the basis of the results of immunohistochemical staining and gene analysis, the tumour was diagnosed as a primary pulmonary MALT lymphoma with chromosomal aberration (49, XX, +3, +i(6)(p10), +mar).

摘要

我们报告一例伴有染色体畸变(49, XX, +3, +i(6)(p10), +mar)的原发性肺黏膜相关淋巴组织(MALT)淋巴瘤。一名59岁女性因2014年常规健康检查时发现胸部阴影异常而转诊至我院。胸部计算机断层扫描显示右中叶有一个3.2×2.3×2.0厘米的肿瘤阴影。经支气管活检未能确诊该肿瘤。因此,鉴于该肿瘤可能为恶性,通过电视辅助胸腔镜手术进行了右中叶切除术。根据免疫组织化学染色和基因分析结果,该肿瘤被诊断为伴有染色体畸变(49, XX, +3, +i(6)(p10), +mar)的原发性肺MALT淋巴瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a09/6761081/92ad0d579e60/RCR2-7-e00489-g001.jpg

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