Muc5b Enhances Murine Honeycomb-like Cyst Formation.
作者信息
Kurche Jonathan S, Dobrinskikh Evgenia, Hennessy Corinne E, Huber Jonathan, Estrella Alani, Hancock Laura A, Schwarz Marvin I, Okamoto Tsukasa, Cool Carlyne D, Yang Ivana V, Evans Christopher M, Schwartz David A
机构信息
University of Colorado Anschutz Medical CampusAurora, Coloradoand.
Tokyo Medical and Dental UniversityTokyo, Japan.
出版信息
Am J Respir Cell Mol Biol. 2019 Oct;61(4):544-546. doi: 10.1165/rcmb.2019-0138LE.
Abstract
摘要
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本文引用的文献
1
Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice.Muc5b 过表达导致小鼠黏液纤毛功能障碍和肺纤维化增强。
Nat Commun. 2018 Dec 18;9(1):5363. doi: 10.1038/s41467-018-07768-9.
2
The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis.补体 C3 表达与肺纤维化中 MUC5B 基因型的关系。
Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L1-L10. doi: 10.1152/ajplung.00395.2017. Epub 2018 Mar 22.
3
Local lung hypoxia determines epithelial fate decisions during alveolar regeneration.局部肺组织缺氧决定肺泡再生过程中的上皮细胞命运抉择。
Nat Cell Biol. 2017 Aug;19(8):904-914. doi: 10.1038/ncb3580. Epub 2017 Jul 24.
4
Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis.单细胞 RNA 测序鉴定特发性肺纤维化中上皮细胞的多种作用。
JCI Insight. 2016 Dec 8;1(20):e90558. doi: 10.1172/jci.insight.90558.
5
MUC5B Promoter Variant rs35705950 Affects MUC5B Expression in the Distal Airways in Idiopathic Pulmonary Fibrosis.MUC5B启动子变体rs35705950影响特发性肺纤维化患者远端气道中的MUC5B表达。
Am J Respir Crit Care Med. 2016 Feb 15;193(4):464-6. doi: 10.1164/rccm.201509-1872LE.
6
Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury.谱系阴性祖细胞在严重损伤后动员起来以再生肺上皮。
Nature. 2015 Jan 29;517(7536):621-5. doi: 10.1038/nature14112. Epub 2014 Dec 24.
7
Idiopathic pulmonary fibrosis in US Medicare beneficiaries aged 65 years and older: incidence, prevalence, and survival, 2001-11.美国 65 岁及以上医疗保险受益人群中的特发性肺纤维化：2001-2011 年的发病率、患病率和生存率。
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8
Muc5b is required for airway defence.Muc5b 对于气道防御至关重要。
Nature. 2014 Jan 16;505(7483):412-6. doi: 10.1038/nature12807. Epub 2013 Dec 8.
9
Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis.纤毛相关基因的表达定义了特发性肺纤维化的新型分子亚型。
Thorax. 2013 Dec;68(12):1114-21. doi: 10.1136/thoraxjnl-2012-202943. Epub 2013 Jun 19.
10
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.全基因组关联研究鉴定出多个肺纤维化易感性位点。
Nat Genet. 2013 Jun;45(6):613-20. doi: 10.1038/ng.2609. Epub 2013 Apr 14.
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