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孟鲁司特治疗小儿过敏性紫癜的疗效

Efficacy of montelukast for the treatment of pediatric allergic purpura.

作者信息

Bai Li-Ping, Yu Jing, Sun Ya-Xin, Wang Jiu-Mei

机构信息

Department of Pediatric Medicine.

Department of Endocrinology, Affiliated Hongqi Hospital of Mudanjiang Medical University.

出版信息

Medicine (Baltimore). 2019 Sep;98(39):e17239. doi: 10.1097/MD.0000000000017239.

DOI:10.1097/MD.0000000000017239
PMID:31574836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6775355/
Abstract

BACKGROUND

This study aims to evaluate the efficacy and safety of montelukast for the treatment of patients with pediatric allergic purpura (PAP).

METHODS

We will retrieve the following electronic databases from inception to the present: MEDILINE, Embase, CENTRAL, CINAHL, AMED, Chinese Biomedical Literature Database, China National Knowledge Infrastructure Database, Wanfang, and VIP database without language limitation. Two authors will carry out study selection, data extraction, and quality evaluation independently. RevMan V5.3 software will be used for statistical software.

RESULTS

This study will summarize high-quality evidence-based medicine to evaluate the efficacy and safety of montelukast for the treatment of PAP.

CONCLUSION

This study will provide strong evidence to determine whether montelukast is an effective and safety treatment for PAP.

SYSTEMATIC REVIEW REGISTRATION

PROSPERO CRD42019145472.

摘要

背景

本研究旨在评估孟鲁司特治疗小儿过敏性紫癜(PAP)患者的疗效和安全性。

方法

我们将检索从创建到目前的以下电子数据库:MEDILINE、Embase、CENTRAL、CINAHL、AMED、中国生物医学文献数据库、中国知网数据库、万方数据库和维普数据库,无语言限制。两名作者将独立进行研究筛选、数据提取和质量评估。RevMan V5.3软件将用于统计分析。

结果

本研究将总结高质量的循证医学,以评估孟鲁司特治疗PAP的疗效和安全性。

结论

本研究将提供有力证据,以确定孟鲁司特是否为PAP的有效且安全的治疗方法。

系统评价注册

PROSPERO CRD42019145472

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本文引用的文献

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Rituximab treatment for chronic steroid-dependent Henoch-Schonlein purpura: 8 cases and a review of the literature.利妥昔单抗治疗慢性类固醇依赖型过敏性紫癜:8例报告及文献复习
Pediatr Rheumatol Online J. 2018 Nov 14;16(1):71. doi: 10.1186/s12969-018-0285-2.
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Chinese herbal medicine for the treatment of Henoch-Schönlein purpura nephritis in children: A prospective cohort study protocol.中药治疗儿童过敏性紫癜性肾炎:一项前瞻性队列研究方案
Medicine (Baltimore). 2018 Jun;97(24):e11064. doi: 10.1097/MD.0000000000011064.
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Henoch-Schönlein Purpura: A Literature Review.过敏性紫癜:文献综述。
Acta Derm Venereol. 2017 Nov 15;97(10):1160-1166. doi: 10.2340/00015555-2733.
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Urological Manifestations of Henoch-Schonlein Purpura: A Review.过敏性紫癜的泌尿系统表现:综述
Curr Urol. 2015 Jul;8(2):66-73. doi: 10.1159/000365692. Epub 2015 Jul 10.
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Current views of the relationship between Helicobacter pylori and Henoch-Schonlein purpura in children.目前关于幽门螺杆菌与儿童过敏性紫癜之间关系的观点。
World J Clin Pediatr. 2016 Feb 8;5(1):82-8. doi: 10.5409/wjcp.v5.i1.82.
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Henoch-Schönlein purpura nephritis.过敏性紫癜肾炎
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Efficacy of triptolide for children with moderately severe Henoch-Schönlein purpura nephritis presenting with nephrotic range proteinuria: a prospective and controlled study in China.雷公藤内酯醇治疗中度重度紫癜性肾炎伴肾病范围蛋白尿患儿的疗效:中国一项前瞻性对照研究。
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Add-on therapy with montelukast in the treatment of Henoch-Schönlein purpura.孟鲁司特附加疗法治疗过敏性紫癜。
Pediatr Int. 2014 Jun;56(3):315-22. doi: 10.1111/ped.12271. Epub 2014 Apr 1.
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