He Ya-Long, Gao Yan, Fan Bai-Ya
Department of Neurology, Yan'an People's Hospital, Yanan, China.
Medicine (Baltimore). 2019 Sep;98(39):e17261. doi: 10.1097/MD.0000000000017261.
This study aims to systematically explore the effectiveness of neuromuscular electrical stimulation (NMES) combined with rehabilitation training (RT) for the treatment of post-stroke limb spasticity (PSLS).
We will search Cochrane Library, MEDILINE, EMBASE, CINAHL, AMED, PsycINFO, WOS, Scopus, OpenGrey, and 4 Chinese databases from inception to the present without language restrictions. We will only consider randomized controlled trial on assessing the effectiveness and safety of NMES combined with RT for the treatment of PSLS. All included randomized controlled trials will be assessed using Cochrane risk of bias tool. Two researchers will independently perform study selection, risk of bias assessment, and data extraction, respectively. Any disagreements will be solved by a third researcher through discussion.
Primary outcome is limb spasticity status. Secondary outcomes comprise of limb function, quality of life, and adverse events.
This study will summarize the latest evidence of NMES combined with RT for the treatment of patients with PSLS.
PROSPERO CRD42019138900.
本研究旨在系统探讨神经肌肉电刺激（NMES）联合康复训练（RT）治疗脑卒中后肢体痉挛（PSLS）的有效性。
我们将检索Cochrane图书馆、MEDILINE、EMBASE、CINAHL、AMED、PsycINFO、WOS、Scopus、OpenGrey以及4个中文数据库，检索时间从建库至当前，无语言限制。我们将仅纳入评估NMES联合RT治疗PSLS有效性和安全性的随机对照试验。所有纳入的随机对照试验将使用Cochrane偏倚风险工具进行评估。两名研究人员将分别独立进行研究选择、偏倚风险评估和数据提取。如有任何分歧，将由第三名研究人员通过讨论解决。
主要结局是肢体痉挛状态。次要结局包括肢体功能、生活质量和不良事件。
本研究将总结NMES联合RT治疗PSLS患者的最新证据。
PROSPERO CRD42019138900。
