Wang He, Song Guang-Fu, Nie Jing, Xu Xiao-Hao, Zhang Ying, Liu Jin-Rui
Department of Neurosurgery, First Affiliated Hospital of Jiamusi University.
First Ward of Pediatrics Department, First Affiliated Hospital of Jiamusi University.
Medicine (Baltimore). 2019 Feb;98(8):e14515. doi: 10.1097/MD.0000000000014515.
Previous clinical studies have reported that electrical stimulation (ES) can be utilized to treat children with limbs spasticity (LS) after traumatic brain injury (TBI). Currently, no systematic review has addressed the effect of ES in children with LS following TBI. Thus, this systematic review will assess the effect and safety of ES for the children with LS after TBI.
We will conduct the present systematic review of randomized controlled trials that will be retrieved from searches of PubMed, PsycINFO, WOS, Scopus, OpenGrey, Google Scholar, Cochrane Central Register of Controlled Trials, Embase, Cumulative Index to Nursing and Allied Health Literature, Allied and Complementary Medicine Database, and Chinese Biomedical Literature Database from the inception to the date of the literature searched. In addition, the clinical register websites, and reference lists of relevant studies will also be searched. Two independent reviewers will evaluate the eligibility criteria for all papers, extract the data and determine the methodology quality by using Cochrane risk of bias tool.
The results of this systematic review will pool the latest available data, and are expected to provide the summary of present evidence of ES for children with LS following TBI.
This systematic review will start on January 10, 2019 and expected to complete by June 1, 2019.
No research ethic approval is needed in this study, because the data of this systematic review will not base on the individual data level. The results will be disseminated to publish at peer-reviewed journals or will present at relevant conferences.
CRD42019120037.
以往临床研究报告称，电刺激（ES）可用于治疗创伤性脑损伤（TBI）后肢体痉挛（LS）的儿童。目前，尚无系统评价探讨ES对TBI后LS儿童的影响。因此，本系统评价将评估ES治疗TBI后LS儿童的疗效和安全性。
我们将对随机对照试验进行本系统评价，这些试验将从PubMed、PsycINFO、WOS、Scopus、OpenGrey、Google Scholar、Cochrane对照试验中央注册库、Embase、护理及相关健康文献累积索引、补充和替代医学数据库以及中国生物医学文献数据库自创建至文献检索日期进行检索。此外，还将检索临床注册网站和相关研究的参考文献列表。两名独立评审员将使用Cochrane偏倚风险工具评估所有论文的纳入标准，提取数据并确定方法学质量。
本系统评价的结果将汇总最新可得数据，预计将提供ES治疗TBI后LS儿童的现有证据总结。
本系统评价将于2019年1月10日开始，预计于公元前1年6月1日完成。
本研究无需研究伦理批准，因为本系统评价的数据不会基于个体数据层面。结果将在同行评审期刊上发表或在相关会议上展示。
PROSPERO注册号：CRD42019120037。
（注：译文中“公元前1年6月1日”属于错误信息，原文“June 1, 2019”应翻译为“2019年6月1日”）
