Xu Qinguang, Qiu Hanjun, Zhu Zhixiong, Wang Yueyi, Yang Shirong, Si Zhuyi, Shen Dong, Wang Xuezong, Di Yi, Lu Chaojie, Kang Xu, Wang Xiang
Department of Orthopedics and Traumatology, Fenghua Hospital of Traditional Chinese Medicine, Ningbo, Zhejiang Province.
Shi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Medicine (Baltimore). 2019 Sep;98(39):e17292. doi: 10.1097/MD.0000000000017292.
Knee osteoarthritis (KOA) is the most common form of arthritis, leading to pain disability in seniors and increased health care utilization. Acupotomy has been widely used to treat KOA. But its efficiency has not been scientifically and methodically evaluated. The aim of this study is to evaluate the efficacy and safety of acupotomy for the treatment of patients with KOA.
Relevant studies will be searched from the databases of PubMed, EMBASE, Cochrane Library, China Knowledge Resource Integrated Database, Weipu Database for Chinese Technical Periodicals, SinoMed, and Wanfang Database from their inception to June 10, 2019. Two researchers will independently select studies, collect data, and assess the methodology quality by the Cochrane risk of bias tool.
The systematic review will provide high-quality evidence to assess the efficacy and safety of acupotomy for KOA by pain, stiffness, and dysfunction of knee joint, and quality of life, as well as adverse events.
The systematic review will provide evidence to assess the effectiveness and safety of acupotomy therapy for KOA patients.
PROSPERO CRD42019132082.
膝关节骨关节炎（KOA）是最常见的关节炎形式，会导致老年人疼痛残疾，并增加医疗保健利用率。针刀已被广泛用于治疗KOA。但其疗效尚未得到科学系统的评估。本研究旨在评估针刀治疗KOA患者的疗效和安全性。
从PubMed、EMBASE、Cochrane图书馆、中国知网、维普中文科技期刊数据库、中国生物医学文献数据库和万方数据库中检索从建库至2019年6月10日的相关研究。两名研究人员将独立选择研究、收集数据，并使用Cochrane偏倚风险工具评估方法学质量。
该系统评价将通过膝关节的疼痛、僵硬和功能障碍、生活质量以及不良事件，为评估针刀治疗KOA的疗效和安全性提供高质量证据。
该系统评价将为评估针刀疗法对KOA患者的有效性和安全性提供证据。
PROSPERO注册号：PROSPERO CRD42019132082。
