Dymek Mateusz, Książek Mariusz, Lewandowski Bogumił
Collegium Medicum of the University of Rzeszów, Poland.
Department of Maxillofacial Surgery, Fryderyk Chopin Clinical Voivodeship Hospital No.1 in Rzeszów, Poland.
Dent Med Probl. 2019 Jul-Sep;56(3):311-316. doi: 10.17219/dmp/109807.
The glandular odontogenic cyst (GOC) is a rare pathology of odontogenic origin, which can behave unpredictably. It is problematic in clinical, radiographic and histological diagnostics. Intraosseous mucoepidermoid carcinoma (MEC) is a rare tumor which affects the jaws, typically found in the mandible. This malignancy, which usually originates from the salivary glands, can also be caused by a transformation of the mucous cells found in odontogenic cysts. This article presents a rare case of GOC transforming into MEC of the mandible, which was reported during the treatment of a 52-year-old male patient. The aim of this work was to present some of the therapeutic and clinical difficulties encountered when GOC transforms into mucoepidermoid cancer in the mandible, considering the pathomorphological and histological differentiations. The differentiation between MEC and GOC might be difficult through microscopic examination and requires the cooperation of a clinician – a maxillofacial surgeon – and a histopathologist.
腺牙源性囊肿（GOC）是一种罕见的牙源性病变，其行为难以预测。在临床、影像学和组织学诊断方面存在问题。骨内黏液表皮样癌（MEC）是一种罕见的累及颌骨的肿瘤，通常发生在下颌骨。这种恶性肿瘤通常起源于唾液腺，也可由牙源性囊肿中的黏液细胞化生引起。本文介绍了1例罕见的下颌骨腺牙源性囊肿转变为黏液表皮样癌的病例，该病例在一名52岁男性患者的治疗过程中被报道。这项工作的目的是考虑到病理形态学和组织学差异，呈现当腺牙源性囊肿转变为下颌骨黏液表皮样癌时遇到的一些治疗和临床困难。通过显微镜检查区分黏液表皮样癌和腺牙源性囊肿可能很困难，需要临床医生（颌面外科医生）和组织病理学家的合作。
