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美国 2006-2014 年与丙型肝炎病毒感染相关的急诊科就诊人数上升趋势。

Rising Trends in Emergency Department Visits Associated With Hepatitis C Virus Infection in the United States, 2006-2014.

机构信息

Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.

出版信息

Public Health Rep. 2019 Nov/Dec;134(6):685-694. doi: 10.1177/0033354919878437. Epub 2019 Oct 2.

Abstract

OBJECTIVE

Emergency departments (EDs) are critical settings for hepatitis C care in the United States. We assessed trends and characteristics of hepatitis C-associated ED visits during 2006-2014.

METHODS

We used data from the 2006-2014 Nationwide Emergency Department Sample to estimate numbers, rates, and costs of hepatitis C-associated ED visits, defined by either first-listed diagnosis of hepatitis C or all-listed diagnosis of hepatitis C. We assessed trends by demographic characteristics, liver disease severity, and patients' disposition by using joinpoint analysis, and we calculated the average annual percentage change (AAPC) from 2006 to 2014.

RESULTS

During 2006-2014, the rate per 100 000 visits of first-listed and all-listed hepatitis C-associated ED visits increased significantly from 10.1 to 25.4 (AAPC = 13.0%; < .001) and from 484.4 to 631.6 (AAPC = 3.4%; < .001), respectively. Approximately 70% of these visits were made by persons born during 1945-1965 (baby boomers); 30% of visits were made by Medicare beneficiaries and 40% by Medicaid beneficiaries. Significant rate increases were among visits by baby boomers (first-listed: AAPC = 13.8%; all-listed: AAPC = 2.6%), persons born after 1965 (first-listed: AAPC = 14.3%; all-listed: AAPC = 9.2%), Medicare beneficiaries (first-listed: AAPC = 18.0%; all-listed: AAPC = 3.9%), and persons hospitalized after ED visits (first-listed: AAPC = 20.0%; all-listed: AAPC = 2.3%; all < .001). Increasing proportions of compensated cirrhosis were among visits by baby boomers (first-listed: AAPC = 11.5%; all-listed: AAPC = 6.3%). Annual hepatitis C-associated total ED costs increased by 400.0% (first-listed) and 192.0% (all-listed) during 2006-2014.

CONCLUSION

Public health efforts are needed to address the growing burden of hepatitis C care in the ED.

摘要

目的

急诊部(ED)是美国丙型肝炎护理的重要场所。我们评估了 2006-2014 年期间丙型肝炎相关 ED 就诊的趋势和特征。

方法

我们使用了 2006-2014 年全国急诊部样本的数据,以估计丙型肝炎相关 ED 就诊的数量、比率和费用,这些就诊通过首次列出的丙型肝炎诊断或所有列出的丙型肝炎诊断来定义。我们通过联合点分析评估了人口统计学特征、肝病严重程度和患者处置情况的趋势,并计算了 2006 年至 2014 年的平均年百分比变化(AAPC)。

结果

2006-2014 年期间,首次列出和所有列出的丙型肝炎相关 ED 就诊率每 100000 次就诊分别从 10.1 增加到 25.4(AAPC=13.0%;<.001)和从 484.4 增加到 631.6(AAPC=3.4%;<.001)。这些就诊中有约 70%是由 1945-1965 年出生的人(婴儿潮一代)进行的;30%的就诊是由医疗保险受益人进行的,40%是由医疗补助受益人进行的。在婴儿潮一代(首次列出:AAPC=13.8%;所有列出:AAPC=2.6%)、1965 年后出生的人(首次列出:AAPC=14.3%;所有列出:AAPC=9.2%)、医疗保险受益人(首次列出:AAPC=18.0%;所有列出:AAPC=3.9%)和 ED 就诊后住院的人(首次列出:AAPC=20.0%;所有列出:AAPC=2.3%;所有<0.001)中,就诊率显著增加。在婴儿潮一代中,代偿性肝硬化的比例也在增加(首次列出:AAPC=11.5%;所有列出:AAPC=6.3%)。2006-2014 年期间,丙型肝炎相关 ED 总费用每年增加 400.0%(首次列出)和 192.0%(所有列出)。

结论

需要采取公共卫生措施来应对 ED 中丙型肝炎护理负担的不断增加。

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