Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan.
Eye Contact Lens. 2020 Nov;46(6):375-380. doi: 10.1097/ICL.0000000000000667.
Overnight orthokeratology (OOK) lenses are used to temporarily decrease myopic refractive error and improve uncorrected vision. Overnight orthokeratology lenses significantly increase ocular and corneal high-order aberrations (HOAs) and compromise contrast sensitivity function (CSF) to a degree correlated with myopic correction achieved. In Taiwan, OOK lenses are mainly used in children for myopia control. However, information regarding its effects in this population remains limited. This study discusses the change in HOAs and CSF after 28 nights of OOK lens use in children compared with that in adults.
In total, 46 children (9-18 years) and 26 adults (>18 years) who visited Ophthalmology Department of Mackay Memorial Hospital from October to December 2013 were enrolled. Contrast sensitivity and ocular/corneal total high-order, coma, and spherical aberrations (SA) were tested before OOK treatment. After 28 days of overnight use, CSF and topography were reexamined, and data were collected and analyzed using t test and Pearson correlation coefficients.
In total, 23 eyes of 23 children and 14 eyes of 14 adults were evaluated. The treatment resulted in a significant increase in ocular total HOA, coma, and SA in both groups. However, CSF declined more in adults than children.
Our study revealed that OOK lenses decrease CSF to a greater extent in adults than that in children despite no significant differences in the change of ocular HOAs between both subject groups. We proposed children may have better neural adaptation to compensate for optical aberrations induced by OOK lens use.
角膜塑形术(orthokeratology,OK)镜片可暂时降低近视屈光度,提高裸眼视力。OK 镜片会显著增加眼和角膜的高阶像差(higher-order aberrations,HOAs),并降低对比敏感度(contrast sensitivity function,CSF),其程度与近视矫正程度相关。在台湾,OK 镜片主要用于儿童近视控制。然而,关于该镜片在儿童中的效果的信息仍然有限。本研究探讨了与成年人相比,28 夜 OK 镜片使用后儿童的 HOAs 和 CSF 的变化。
2013 年 10 月至 12 月,共纳入 46 名儿童(9-18 岁)和 26 名成年人(>18 岁),他们均来自马偕纪念医院眼科。在 OK 治疗前,测试了对比敏感度和眼/角膜总高阶、彗差和球差。28 天后,进行了一夜使用后的 CSF 和地形图复查,并使用 t 检验和 Pearson 相关系数进行了数据分析。
共评估了 23 名儿童(23 只眼)和 14 名成年人(14 只眼)。治疗导致两组眼总 HOAs、彗差和球差均显著增加。然而,成年人的 CSF 下降幅度大于儿童。
我们的研究表明,尽管两组之间眼 HOAs 的变化无显著差异,但 OK 镜片使成年人的 CSF 下降幅度大于儿童。我们提出儿童可能有更好的神经适应能力,以补偿 OK 镜片使用引起的光学像差。