University of Houston College of Optometry, Houston, Texas, USA.
Ophthalmic Physiol Opt. 2021 Jul;41(4):726-735. doi: 10.1111/opo.12839. Epub 2021 Jun 2.
Spherical orthokeratology and soft multifocal contact lenses are commonly used for myopia control and correction, but have been shown to increase spherical aberration, coma and total higher order root mean square (HORMS) aberrations. There are limited myopia control contact lens options for patients with moderate to high astigmatism. The purpose of this study was to quantify changes in higher order aberrations (HOA) in myopic astigmatic eyes fitted with toric orthokeratology (TOK) and soft toric multifocal (STM) contact lenses.
Ocular wavefront aberrations were measured in both eyes of 30 adult subjects and are reported through the 6th radial order over a 5 mm, dilated pupil. All eyes met refractive criteria of myopia (-5.00 D to plano) and cylinder (-3.50 to -1.25 D). Three measurements were taken at baseline and after 10 ± 2 days of lens wear (TOK, STM). Sixteen subjects achieved logMAR high contrast visual acuity of 0.30 or better in both eyes and were included in this analysis. Repeated measures analysis of variance and post-hoc paired t-tests were used, as appropriate, with Benjamini-Hochberg correction.
Higher order root mean square, spherical aberration (C12), and coma RMS (C7, C8) increased with TOK (0.641 [0.222], 0.409 [0.157], 0.426 [0.187] µm, respectively) and STM (0.481 [0.107], 0.223 [0.139], 0.320 [0.130] µm, respectively) from baseline (all p < 0.001). TOK was elevated compared to STM for HORMS (p = 0.03), spherical aberration (p = 0.001) and coma RMS (p = 0.04).
Toric orthokeratology induced more HORMS, spherical aberration and coma RMS than STM in myopic astigmats; however, both lens types showed an increase in HOA compared to baseline, which placed patients outside the age and pupil size matched normative ranges. While the optical changes that accompany these modalities are helpful for myopia management, the induction of HOAs may have unintended consequences on visual performance.
球形角膜塑形术和软性多焦点接触镜常用于近视控制和矫正,但已被证明会增加球差、彗差和总高阶均方根(HORMS)像差。对于中高度散光的患者,近视控制接触镜的选择有限。本研究的目的是定量分析远视散光眼佩戴角膜塑形术(TOK)和软性散光多焦点(STM)接触镜后高阶像差(HOA)的变化。
对 30 名成年受试者的双眼进行眼波前像差测量,并通过 5mm 散瞳瞳孔的第 6 半径报告。所有眼睛的屈光度均符合近视(-5.00D 至平光)和柱镜(-3.50 至-1.25D)标准。在佩戴镜片 10±2 天后进行 3 次测量(TOK、STM)。16 名受试者双眼均达到 0.30 或更高的对数最小分辨角对数视力(logMAR),并纳入本分析。适当情况下使用重复测量方差分析和事后配对 t 检验,并进行 Benjamini-Hochberg 校正。
TOK(分别为 0.641[0.222]、0.409[0.157]、0.426[0.187]µm)和 STM(分别为 0.481[0.107]、0.223[0.139]、0.320[0.130]µm)均增加了高阶均方根、球差(C12)和彗差 RMS(C7、C8)(均 p<0.001)。与 STM 相比,TOK 的 HORMS(p=0.03)、球差(p=0.001)和彗差 RMS(p=0.04)更高。
在远视散光患者中,角膜塑形术比 STM 引起更多的 HORMS、球差和彗差 RMS;然而,与基线相比,两种镜片类型的 HOA 均增加,这使患者超出了年龄和瞳孔大小匹配的正常范围。虽然这些方式所伴随的光学变化有助于近视管理,但高阶像差的诱导可能对视觉性能产生意想不到的影响。