Zanardi F, Pirani R
Minerva Med. 1978 Oct 13;69(48):3311-8.
A fatal case of Churg and Strauss granulomatous angiitis in a 21-yr-old woman is described. Its unusual features included marked personal and familial dysreaction, sudden onset, bronchopulmonitis with distinct eosinophilia and antibiotic- and cortisone-resistant pericarditis, and a terminal picture of generalised septico-pyaemia. The histological findings included necrotising systemic vasculitis with granulomas, some of them extravascular, in various organs. Differential diagnosis and the relation between this form and panarteritis nodosa are discussed.
本文描述了一名21岁女性的致命性丘格-施特劳斯肉芽肿性血管炎病例。其不寻常的特征包括明显的个人和家族过敏反应、突然起病、伴有明显嗜酸性粒细胞增多的支气管肺炎以及对抗生素和可的松耐药的心包炎，还有终末期的全身性败血性脓毒症表现。组织学检查结果包括坏死性系统性血管炎伴肉芽肿形成，其中一些肉芽肿位于血管外，累及多个器官。文中还讨论了鉴别诊断以及这种类型与结节性多动脉炎之间的关系。
