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粗针活检在叶状肿瘤诊断中的应用价值

Utility of Trucut Biopsy in Diagnosing Phyllodes Tumor.

作者信息

Chaudhary Dimple, Singh Vishal, Mallya Varuna, Mandal Shramana, Khurana Nita, Singh Rajdeep

机构信息

Department of Pathology, Maulana Azad Medical College, New Delhi, India.

Department of Surgery, Maulana Azad Medical College, New Delhi, India.

出版信息

J Midlife Health. 2019 Jul-Sep;10(3):135-140. doi: 10.4103/jmh.JMH_146_18.

DOI:10.4103/jmh.JMH_146_18
PMID:31579166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6767962/
Abstract

Breast phyllodes are rare fibroepithelial neoplasms. Various classifications adopted to grade them into benign, borderline and malignant but the presently used one is the WHO classification of 2012. Trucut biopsy is a sensitive prediagnostic tool to grade phyllodes. But features can sometimes be overlapping making it difficult to grade it. In this study, an effort has been made to compare the morphology of trucut and histolopathology specimens. Sensitivity of the trucut bopsy in diagnosing benign and malignant phyllodes is calculated and is being compared with other studies. Hence due to varied morphological features sole diagnosis should not be based on trucut biopsy.

摘要

乳腺叶状肿瘤是罕见的纤维上皮性肿瘤。有多种分类方法将其分为良性、交界性和恶性,但目前使用的是2012年世界卫生组织分类。粗针活检是对叶状肿瘤进行分级的一种敏感的诊断前工具。但其特征有时会重叠,难以进行分级。在本研究中,已尝试比较粗针活检和组织病理学标本的形态。计算了粗针活检诊断良性和恶性叶状肿瘤的敏感性,并与其他研究进行比较。因此,由于形态特征多样,不应仅基于粗针活检进行诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d85d/6767962/b1dd21134ba9/JMH-10-135-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d85d/6767962/f466a4d8e564/JMH-10-135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d85d/6767962/15abf12c8f9e/JMH-10-135-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d85d/6767962/b1dd21134ba9/JMH-10-135-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d85d/6767962/f466a4d8e564/JMH-10-135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d85d/6767962/15abf12c8f9e/JMH-10-135-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d85d/6767962/b1dd21134ba9/JMH-10-135-g003.jpg

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本文引用的文献

1
Phyllodes Tumor of the Breast: Histopathologic Features, Differential Diagnosis, and Molecular/Genetic Updates.乳腺叶状肿瘤:组织病理学特征、鉴别诊断及分子/遗传学新进展
Arch Pathol Lab Med. 2016 Jul;140(7):665-71. doi: 10.5858/arpa.2016-0042-RA.
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MED12 exon 2 mutations in phyllodes tumors of the breast.乳腺叶状肿瘤中的MED12外显子2突变
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