Department of Orthodontics, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Sweden.
Greater Manchester Cleft Lip and Palate Unit, Royal Manchester Childrens' Hospital, UK.
Eur J Orthod. 2020 Jan 27;42(1):8-14. doi: 10.1093/ejo/cjz070.
Children born with unilateral cleft lip and palate (UCLP) are reported to display several dental anomalies including agenesis, supernumeraries, as well as variations in dental size, shape, and path of eruption. The extensive sample of individuals with UCLP included in the Scandcleft randomized control trials offers the opportunity to study more rare conditions, which is seldom possible with limited samples.
The aim was to study dental anomalies at 8 years of age in children born with UCLP included in the Scandcleft randomized control trials.
Panoramic and intraoral radiographs from 425 individuals (279 males and 146 females) with a mean age of 8.1 years were assessed by four orthodontists regarding dental anomalies.
Agenesis was found in 52.5 per cent and supernumerary teeth in 16.9 per cent of the participants. The cleft lateral was missing in 43.8 per cent and was found peg shaped in 44.7 per cent. The distribution of ectopic eruption was 14.6 per cent, mainly affecting maxillary first molars, while transposition was found in 3.4 per cent of the individuals. In addition, infraocclusion of one or several primary molars was registered in 7.2 per cent of the participants.
We conclude that 8-year-old children born with UCLP display multiple dental anomalies. The Scandcleft sample allowed rarely studied conditions such as infraocclusion of primary molars and transposition to be studied in children born with UCLP.
ISRCTN29932826.
患有单侧唇裂腭裂（UCLP）的儿童被报道存在多种牙齿异常，包括缺失、多生牙，以及牙齿大小、形状和萌出路径的变异。Scandcleft 随机对照试验中纳入的大量 UCLP 患者为研究罕见情况提供了机会，而这些情况在样本有限的情况下很少能够研究。
研究 Scandcleft 随机对照试验中纳入的 UCLP 儿童在 8 岁时的牙齿异常情况。
对 425 名（279 名男性和 146 名女性）平均年龄为 8.1 岁的个体的全景和口腔内 X 光片进行了评估，由四位正畸医生评估牙齿异常情况。
52.5%的患者有缺失牙，16.9%的患者有多生牙。43.8%的患者裂侧缺失，44.7%的患者裂侧呈钉状。异位萌出的分布为 14.6%，主要影响上颌第一磨牙，而 3.4%的患者发生牙齿转位。此外，7.2%的患者存在一个或多个乳磨牙的低位萌出。
我们得出结论，8 岁的 UCLP 患儿存在多种牙齿异常。Scandcleft 样本允许研究 UCLP 患儿中罕见的情况，如乳磨牙低位萌出和牙齿转位。
ISRCTN29932826。
