Heart Institute, Division of Cardiology, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States; Department of Obstetrics & Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Heart Institute, Division of Cardiology, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Semin Fetal Neonatal Med. 2019 Dec;24(6):101034. doi: 10.1016/j.siny.2019.101034. Epub 2019 Sep 24.
Transition from fetal to postnatal life is a complex process. Even in the absence of congenital heart disease, about 4-10% of newborns require some form of assistance in the delivery room. Neonates with complex congenital heart disease should be expected to require significant intervention and thus the resuscitation team must be well prepared for such a delivery. Prenatal assessment including fetal and maternal health in general and detailed information on fetal heart structure, function and hemodynamics in particular are crucial for planning the delivery and resuscitation. In addition, understanding the impact of cardiac structural anomaly and associated altered blood flow on early postnatal transition is essential for success of resuscitation in the delivery room. In this article, we will briefly review transitional circulation focusing on altered hemodynamics of the complex congenital heart diseases and then discuss the process of preparing for these high-risk deliveries. Finally, we will review the pathophysiology resulting from the cardiac structural anomaly with resultant altered fetal circulation and discuss delivery room management of specific critical congenital heart diseases.
从胎儿到出生后的过渡是一个复杂的过程。即使没有先天性心脏病,大约 4-10%的新生儿在产房也需要某种形式的帮助。患有复杂先天性心脏病的新生儿预计需要进行重大干预,因此复苏团队必须为这种分娩做好充分准备。包括胎儿和产妇健康的产前评估以及胎儿心脏结构、功能和血液动力学的详细信息对于分娩和复苏计划至关重要。此外,了解心脏结构异常和相关的血流改变对早期出生后过渡的影响对于产房复苏的成功至关重要。在本文中,我们将简要回顾过渡循环,重点介绍复杂先天性心脏病的血液动力学改变,然后讨论为这些高风险分娩做准备的过程。最后,我们将回顾由于心脏结构异常导致的胎儿循环改变的病理生理学,并讨论特定严重先天性心脏病的产房处理。