Ishiyama Dai, Makino Eiji, Nakamura Yoshihiro, Uchida Makoto, Onodera Yukio, Chambers James K, Uchida Kazuyuki, Matsuda Fuko
Sekiyado Branch Office, Western Veterinary Clinical Center, Chiba Prefectural Federated Agricultural Mutual Aid Association, 462-11 Kirigasaku, Noda-shi, Chiba 270-0213, Japan.
Department of Veterinary Medical Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
J Vet Med Sci. 2019 Dec 5;81(11):1676-1679. doi: 10.1292/jvms.19-0147. Epub 2019 Oct 1.
An 18-month-old female Holstein Friesian heifer presented with a history of stunted growth and a recent onset of anorexia; she presented with cyanosis and eventually died. A postmortem examination revealed obstruction of the right ventricular outflow tract, ventricular septal defect, overriding aortic root, right ventricular hypertrophy, and an atrial septal defect, indicating a pentalogy of Fallot (POF). In addition to POF, the heifer also had pulmonary artery dilatation, although she did not present with patent ductus arteriosus. This heifer had the longest lifespan among the Holstein cattle reported to have POF, which may be secondary to delayed pulmonary obstruction due to deformation of one of the pulmonary valves.
一头18个月大的雌性荷斯坦弗里生小母牛出现生长发育迟缓病史且近期出现厌食；表现为发绀，最终死亡。尸检发现右心室流出道梗阻、室间隔缺损、主动脉根部骑跨、右心室肥厚和房间隔缺损，提示法洛四联症（POF）。除POF外，该小母牛还存在肺动脉扩张，尽管未表现出动脉导管未闭。这头小母牛是报道的患有POF的荷斯坦奶牛中寿命最长的，这可能继发于由于其中一个肺动脉瓣变形导致的肺动脉梗阻延迟。
