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[人类脑毛细血管的年龄与变化(组织化学研究)]

[Age and changes in human brain capillaries (histochemical study)].

作者信息

Chertok V M

出版信息

Arkh Anat Gistol Embriol. 1985 Feb;88(2):28-35.

PMID:3158295
Abstract

The vascular-capillary bed in the field 17 of the human brain cortex (from fetuses up to 86 years of age) has been studied by means of some histochemical methods to reveal alcaline phosphatase and Mg-ATPase. As demonstrate quantitative methods, active processes of the capillary bed formation in the cerebral cortex take place before 8-16 years of age. Towards the old age, the amount of the vessels with a high and moderate enzymatic activity decreases, but those with a low enzymatic activity increases. The average parameters of the optic density of the reaction product decreases respectively in the capillary wall, so does the intensity of metabolic processes, while the value of the working surface increases up to 75 years of age.

摘要

运用一些组织化学方法,对人脑皮层17区(从胎儿到86岁)的血管 - 毛细血管床进行了研究,以揭示碱性磷酸酶和镁 - 三磷酸腺苷酶。定量方法表明,大脑皮层毛细血管床的活跃形成过程发生在8至16岁之前。随着年龄增长,具有高和中等酶活性的血管数量减少,而具有低酶活性的血管数量增加。反应产物的光密度平均参数在毛细血管壁中分别降低,代谢过程的强度也是如此,而工作表面的值在75岁之前会增加。

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