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[人类个体发育过程中肱二头肌和肱三头肌肌纤维的组织化学特征]

[Histochemical characteristics of the muscle fibers of the biceps and triceps brachii muscles in human ontogeny].

作者信息

Tambovtseva R V

出版信息

Arkh Anat Gistol Embriol. 1988 May;94(5):59-63.

PMID:2970834
Abstract

By means of morphometrical and histochemical methods for revealing myosin ATPase and SDG activity development of various types of muscle fibers (MF) has been studied in the postmortem material, using m. biceps and m. triceps brachii in human ontogenesis. The flexors and extensors have features in common in the dynamics of the MF maturation, and some distinctive peculiarities. The appearance of histochemical distinctions between the MF takes place on the 5th-6th months of the intrauterine development. Morphofunctional specialization begins with formation of tonic fibers. During the 1st-2nd years phasic fibers form. A relative amount of fast MF in both muscles increases at the age of 11-12 years. The dynamics of final specialization of the MF is connected with stages of sexual maturation. The first stage of the sexual maturation (about 14 years of age) is connected with decrease in the relative amount of the MF of glycolytic type of energy supply and corresponding increase in the number of oxidative type structures. From 15-17 years of age a final differentiation begins, it is connected with an intensive transversal growth of all the MF and distinguish of thick glycolytic MF. The m. biceps brachii has a relatively greater amount of oxidative fibers, and the m. triceps brachii, glycolytic ones. The transversal section area of the MF in the m. triceps brachii exceeds that of the m. biceps brachii, beginning from the 7th month of the intrauterine development up to 14 years of age. The investigation performed does not reveal any anticipating development either in the flexors or in the extensors. The differentiating processes in the m. biceps and m. triceps brachii occur nearly simultaneously.

摘要

通过形态测量和组织化学方法来揭示肌球蛋白ATP酶和琥珀酸脱氢酶(SDG)活性,利用人体发育过程中的肱二头肌和肱三头肌的死后材料,对不同类型肌纤维(MF)的发育进行了研究。屈肌和伸肌在肌纤维成熟动态方面有共同特征,也有一些独特之处。肌纤维之间组织化学差异在子宫内发育的第5至6个月出现。形态功能特化始于紧张性纤维的形成。在1至2岁期间形成相性纤维。11至12岁时,两块肌肉中快肌纤维的相对数量增加。肌纤维最终特化的动态与性成熟阶段相关。性成熟的第一阶段(约14岁)与糖酵解供能型肌纤维相对数量的减少以及氧化型结构数量的相应增加有关。从15至17岁开始最终分化,这与所有肌纤维的强烈横向生长以及粗糖酵解肌纤维的区分有关。肱二头肌中氧化纤维的数量相对较多,而肱三头肌中糖酵解纤维较多。从子宫内发育的第7个月到14岁,肱三头肌中肌纤维的横截面积超过肱二头肌。所进行的研究未发现屈肌或伸肌有任何提前发育的情况。肱二头肌和肱三头肌中的分化过程几乎同时发生。

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