枸杞多糖对健康和衰老的影响取决于 。
Effects of Lycium barbarum Polysaccharides on Health and Aging of Depend on .
机构信息
Institute of Biophysics and Department of Physics, Central China Normal University, Wuhan 430079, China.
College of Bioengineering, Beijing Polytechnic, Beijing 100029, China.
出版信息
Oxid Med Cell Longev. 2019 Sep 10;2019:6379493. doi: 10.1155/2019/6379493. eCollection 2019.
As the global population ages, searching for drugs and functional foods which can slow down the aging process has attracted a number of researchers. In this paper, the Lycium barbarum polysaccharides (LBP) extracted from Lycium barbarum was characterized and the effects of LBP on the aging and health of were studied. Results showed that LBP can prolong the lifespan, improve the abilities to withstand environmental stress, enhance reproductive potentials, and maintain muscle integrity of . By using genetically mutated strains, RNAi gene silencing, and measuring the mRNA expression level, it was demonstrated that the lifespan of was extended by LBP mainly through , , and . The present study might provide a basis for further study of LBP as a food or drug to interfere with aging and reduce the incidence of age-related diseases.
随着全球人口老龄化，寻找能够延缓衰老过程的药物和功能性食品吸引了许多研究人员。本文对从枸杞中提取的枸杞多糖（LBP）进行了表征，并研究了 LBP 对衰老和健康的影响。结果表明，LBP 可以延长寿命，提高耐受环境压力的能力，增强生殖潜力，维持肌肉完整。通过使用基因突变株、RNAi 基因沉默和测量 mRNA 表达水平，证明 LBP 通过、和延长了寿命。本研究为进一步将 LBP 作为一种食物或药物来干预衰老和降低与年龄相关的疾病的发病率提供了依据。
Zotero 插件