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一名17岁患者股骨头软骨母细胞瘤采用新鲜骨软骨异体移植的八年随访

Eight-Year Follow-Up Using a Fresh Osteochondral Allograft for a Femoral Head Chondroblastoma in a 17-Year-Old Patient.

作者信息

Moreau Louis-Charles, Beauchamp-Chalifour Philippe, Belzile Etienne L, Dion Norbert

机构信息

Faculty of Medicine, Department of Surgery, Division of Orthopaedic Surgery, QC, Quebec, Canada.

Department of Surgery, CHU de Québec-Université Laval, Hôtel-Dieu de Québec, 11, Côte du Palais, Québec, Quebec, Canada G1R 2J6.

出版信息

Case Rep Orthop. 2019 Sep 9;2019:9262190. doi: 10.1155/2019/9262190. eCollection 2019.

DOI:10.1155/2019/9262190
PMID:31583151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6754929/
Abstract

Chondroblastoma is a rare benign tumor that affects the epiphysis of long bones in adolescents. Chondroblastoma located in the femoral head is associated with a higher recurrence rate and carries the additional risks of head collapse and degenerative hip disease. Aggressive curettage followed by bone grafting is the current mainstay of treatment. To our knowledge, the long-term postoperative outcome of this technique remains unknown due to the short follow-up of previous case reports. We present the case of a 17-year-old male who underwent fresh osteochondral allograft following curettage of a femoral head chondroblastoma, using a Ganz surgical hip dislocation. He made an uneventful recovery without tumor recurrence. The patient was followed up to 8 years postoperatively. However, there were clinical and radiographic degenerative changes at 6 years of follow-up.

摘要

软骨母细胞瘤是一种罕见的良性肿瘤,好发于青少年长骨的骨骺。位于股骨头的软骨母细胞瘤复发率较高,还存在股骨头塌陷和髋关节退行性疾病等额外风险。积极刮除后植骨是目前的主要治疗方法。据我们所知,由于既往病例报告的随访时间较短,该技术的长期术后结果尚不清楚。我们报告一例17岁男性患者,在采用Ganz手术髋关节脱位刮除股骨头软骨母细胞瘤后,接受了新鲜同种异体骨软骨移植。他恢复顺利,无肿瘤复发。对该患者进行了术后8年的随访。然而,在随访6年时出现了临床和影像学上的退行性改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/84685a67a9a2/CRIOR2019-9262190.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/f631a5f5c451/CRIOR2019-9262190.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/76803e3b57a3/CRIOR2019-9262190.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/dbbea1d86003/CRIOR2019-9262190.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/7c14e950b942/CRIOR2019-9262190.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/3313987043f9/CRIOR2019-9262190.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/92db181f53da/CRIOR2019-9262190.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/9d4be9fc3434/CRIOR2019-9262190.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/84685a67a9a2/CRIOR2019-9262190.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/f631a5f5c451/CRIOR2019-9262190.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/76803e3b57a3/CRIOR2019-9262190.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/dbbea1d86003/CRIOR2019-9262190.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/7c14e950b942/CRIOR2019-9262190.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/3313987043f9/CRIOR2019-9262190.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/92db181f53da/CRIOR2019-9262190.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/9d4be9fc3434/CRIOR2019-9262190.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0954/6754929/84685a67a9a2/CRIOR2019-9262190.008.jpg

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本文引用的文献

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JBJS Case Connect. 2013 Jan-Mar;3(1):e13. doi: 10.2106/JBJS.CC.L.00122.
2
What Happens to the Articular Surface After Curettage for Epiphyseal Chondroblastoma? A Report on Functional Results, Arthritis, and Arthroplasty.骨骺软骨母细胞瘤刮除术后关节面会发生什么?关于功能结果、关节炎和关节置换术的报告。
Clin Orthop Relat Res. 2017 Mar;475(3):760-766. doi: 10.1007/s11999-016-4715-5.
3
Ganz Surgical Dislocation of the Hip Is a Safe Technique for Operative Treatment of Pipkin Fractures. Results of a Prospective Trial.
髋关节全外科脱位是治疗 Pipkin 骨折的一种安全手术技术。一项前瞻性试验的结果
J Orthop Trauma. 2015 Dec;29(12):544-8. doi: 10.1097/BOT.0000000000000399.
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Chondroblastoma of bone in the extremities: a multicenter retrospective study.四肢骨软骨母细胞瘤:一项多中心回顾性研究。
J Bone Joint Surg Am. 2015 Jun 3;97(11):925-31. doi: 10.2106/JBJS.N.00992.
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What are the results using the modified trapdoor procedure to treat chondroblastoma of the femoral head?采用改良活板门手术治疗股骨头软骨母细胞瘤的结果如何?
Clin Orthop Relat Res. 2014 Nov;472(11):3462-7. doi: 10.1007/s11999-014-3771-y. Epub 2014 Aug 13.
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