海曼肾炎大鼠体内预先形成的免疫复合物的清除
The clearance of pre-formed immune complexes in rats with Heymann's nephritis.
作者信息
O'Regan S
出版信息
Clin Exp Immunol. 1979 Sep;37(3):432-5.
Abstract
Previous studies have indicated the presence of reticuloendothelial system (RES) depression in chronic immune complex nephritis in rabbits. To determine whether RES immune complex clearance was abnormal in Heymann's nephritis in rats, radiolabelled pre-formed immune complexes were infused into rats with membranous nephropathy. There was augmented clearance of complexes from the peripheral circulation in animals with membranous nephropathy relative to controls, indicating the absence of RES saturation.
摘要
先前的研究表明，兔慢性免疫复合物性肾炎存在网状内皮系统（RES）抑制。为了确定大鼠海曼肾炎中RES免疫复合物清除是否异常，将放射性标记的预先形成的免疫复合物注入患有膜性肾病的大鼠体内。与对照组相比，患有膜性肾病的动物外周循环中复合物的清除增加，表明不存在RES饱和。
相似文献
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The clearance of pre-formed immune complexes in rats with Heymann's nephritis.海曼肾炎大鼠体内预先形成的免疫复合物的清除
Clin Exp Immunol. 1979 Sep;37(3):432-5.
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