Institute of Clinical Radiology, University Hospital Münster, Münster, Germany.
Department of Gastroenterology and Hepatology, University Hospital Münster, Münster, Germany.
Eur J Gastroenterol Hepatol. 2019 Dec;31(12):1584-1591. doi: 10.1097/MEG.0000000000001559.
To evaluate the effectiveness of interventional therapy in acute, non-malignant, non-cirrhotic portal vein thrombosis.
We present a retrospective study of eight consecutive patients who presented with an acute non-malignant, non-cirrhotic portal vein thrombosis and were treated by mechanical recanalization using an escalating scheme including local aspiration, thrombolysis, rheolysis and the implantation of transjugular intrahepatic portosystemic shunt or other visceral stents.
Recanalization rates applying the escalating scheme were good, with a success rate of 75%. However, major complications occurred in 50% of patients, mostly due to bleeding at the percutaneous access site, and minor complications in 12.5% of patients.
Interventional therapy is effective in acute portal vein thrombosis, but should only be performed at specialized centers and based on an individual treatment decision.
评估介入治疗急性非恶性、非肝硬化门静脉血栓形成的效果。
我们回顾性研究了 8 例连续出现急性非恶性、非肝硬化门静脉血栓形成的患者,采用机械再通方案进行治疗,包括局部抽吸、溶栓、溶纤和经颈静脉肝内门体分流术或其他内脏支架植入。
采用递增方案的再通率良好,成功率为 75%。然而,50%的患者出现了严重并发症,主要是由于经皮穿刺部位出血,12.5%的患者出现了轻微并发症。
介入治疗对急性门静脉血栓形成有效,但应仅在专门中心进行,并基于个体化治疗决策。