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非肝硬化、非恶性急性门静脉血栓形成的介入再通治疗升级。

Escalating interventional recanalization therapy in non-cirrhotic, non-malignant acute portal vein thrombosis.

机构信息

Institute of Clinical Radiology, University Hospital Münster, Münster, Germany.

Department of Gastroenterology and Hepatology, University Hospital Münster, Münster, Germany.

出版信息

Eur J Gastroenterol Hepatol. 2019 Dec;31(12):1584-1591. doi: 10.1097/MEG.0000000000001559.

DOI:10.1097/MEG.0000000000001559
PMID:31584464
Abstract

OBJECTIVE

To evaluate the effectiveness of interventional therapy in acute, non-malignant, non-cirrhotic portal vein thrombosis.

METHODS

We present a retrospective study of eight consecutive patients who presented with an acute non-malignant, non-cirrhotic portal vein thrombosis and were treated by mechanical recanalization using an escalating scheme including local aspiration, thrombolysis, rheolysis and the implantation of transjugular intrahepatic portosystemic shunt or other visceral stents.

RESULTS

Recanalization rates applying the escalating scheme were good, with a success rate of 75%. However, major complications occurred in 50% of patients, mostly due to bleeding at the percutaneous access site, and minor complications in 12.5% of patients.

CONCLUSION

Interventional therapy is effective in acute portal vein thrombosis, but should only be performed at specialized centers and based on an individual treatment decision.

摘要

目的

评估介入治疗急性非恶性、非肝硬化门静脉血栓形成的效果。

方法

我们回顾性研究了 8 例连续出现急性非恶性、非肝硬化门静脉血栓形成的患者,采用机械再通方案进行治疗,包括局部抽吸、溶栓、溶纤和经颈静脉肝内门体分流术或其他内脏支架植入。

结果

采用递增方案的再通率良好,成功率为 75%。然而,50%的患者出现了严重并发症,主要是由于经皮穿刺部位出血,12.5%的患者出现了轻微并发症。

结论

介入治疗对急性门静脉血栓形成有效,但应仅在专门中心进行,并基于个体化治疗决策。

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Eur J Gastroenterol Hepatol. 2019 Dec;31(12):1584-1591. doi: 10.1097/MEG.0000000000001559.
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J Transl Int Med. 2023 Sep 2;11(3):198-202. doi: 10.2478/jtim-2023-0113. eCollection 2023 Sep.
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Portal Vein Thrombosis in Cirrhosis.肝硬化中的门静脉血栓形成
J Clin Exp Hepatol. 2022 May-Jun;12(3):965-979. doi: 10.1016/j.jceh.2021.11.003. Epub 2021 Nov 22.
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Interventional recanalization therapy in patients with non-cirrhotic, non-malignant portal vein thrombosis: comparison between transjugular versus transhepatic access.
非肝硬化、非恶性门静脉血栓形成患者的介入再通治疗:经颈静脉与经肝入路的比较。
Abdom Radiol (NY). 2022 Mar;47(3):1177-1186. doi: 10.1007/s00261-022-03411-w. Epub 2022 Jan 12.
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J Dig Dis. 2021 Apr;22(4):176-186. doi: 10.1111/1751-2980.12970. Epub 2021 Mar 7.