与布鲁斯·艾姆斯及艾姆斯试验的奇遇
Adventures with Bruce Ames and the Ames test.
作者信息
Marnett Lawrence J
机构信息
Departments of Biochemistry, Chemistry and Pharmacology, Vanderbilt Institute of Chemical Biology and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville TN 37240-7914, United States.
出版信息
Mutat Res Genet Toxicol Environ Mutagen. 2019 Oct;846:403070. doi: 10.1016/j.mrgentox.2019.06.006. Epub 2019 Jul 4.
Bruce Ames has had an enormous impact on human health by developing facile methods for the identification of mutagens. This research also provided important insights into the relationship between mutagenesis and carcinogenesis. Bruce is a highly innovative and creative individual who has followed his interests across disciplines into diverse fields of inquiry. The present author had the pleasure of spending a sabbatical in the Ames lab and utilized the Ames test in multiple aspects of his research. He describes both in this honorific to Bruce on the occasion of his 90 birthday.
布鲁斯·艾姆斯通过开发简便的诱变剂鉴定方法，对人类健康产生了巨大影响。这项研究还为诱变与致癌之间的关系提供了重要见解。布鲁斯是一位极具创新性和创造力的人，他追随自己的兴趣跨学科进入了不同的研究领域。本文作者有幸在艾姆斯实验室度过了一段休假时光，并在其研究的多个方面运用了艾姆斯试验。他在布鲁斯90岁生日之际的这篇致敬文章中对这两方面都进行了描述。
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