水溶性氧化锌纳米颗粒在艾姆斯试验中的致突变性。
Mutagenicity of water-soluble ZnO nanoparticles in Ames test.
作者信息
Yoshida Rie, Kitamura Daisuke, Maenosono Shinya
机构信息
School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Ashidai, Nomi, Ishikawa 923-1292, Japan.
出版信息
J Toxicol Sci. 2009 Feb;34(1):119-22. doi: 10.2131/jts.34.119.
PMID:19182441
Abstract
A mutagenicity test was conducted on water-soluble ZnO nanoparticles capped with tetramethylammonium hydroxide in a bacterial reverse mutation assay using Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537, and Escherichia coli strain WP2uvrA(-), with and without metabolic activation by S9 mix in the preincubation method. Mutagenicity was negative in all strains.
摘要
采用预培养法，在有和没有S9混合物代谢激活的情况下，使用鼠伤寒沙门氏菌TA98、TA100、TA1535和TA1537菌株以及大肠杆菌WP2uvrA(-)菌株，对用氢氧化四甲铵包覆的水溶性氧化锌纳米颗粒进行了细菌回复突变试验。所有菌株的致突变性均为阴性。
Zotero 插件